SCHEMBL538647

SCHEMBL538647

C=CN1CCC(C)(C)CC1=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 6/20 0.33
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15957869 0.80
SCHEMBL20997436 0.80 KDM4E (0.33)
SCHEMBL1535703 0.79 PLA2G7 (0.31) GRM5
SCHEMBL16168308 0.75 GAA (0.33)
SCHEMBL20841198 0.74
SCHEMBL21205443 0.74 KDM4E (0.32)
SCHEMBL23612406 0.73
SCHEMBL632711 0.71
SCHEMBL21467021 0.71 BRD4 (0.31)
SCHEMBL7951903 0.70 ALDH1A1 (0.36) PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 821 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12638614-B2 Method for making silicone hydrogel contact lenses ALCON INC. (CH) 2026-05-26 US claimed
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-05-14 US claimed
US-12595368-B2 UV/HEVL-filtering contact lenses ALCON INC. (CH) 2026-04-07 US claimed
EP-4713721-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-03-25 EP claimed
EP-4707315-A1 COPOLYMER, COMPOSITION AND USE THEREOF Beijing Mapu New Materials Co., Ltd. (CN) 2026-03-11 EP claimed
US-12570784-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-03-10 US claimed
EP-3759528-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
EP-4514596-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
US-20250347826-A1 METHOD FOR PRODUCING WETTABLE SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-11-13 US claimed
US-6926965-B2 LbL-coated medical device and method for making the same NOVARTIS AG (CH) 2005-08-09 US claimed
EP-1539263-A1 LBL-COATED MEDICAL DEVICE AND METHOD FOR MAKING THE SAME Novartis AG (CH) 2005-06-15 EP claimed
US-20040067365-A1 LbL-coated medical device and method for making the same ALCON INC. (CH) 2004-04-08 US claimed
WO-2004024203-A1 LBL-COATED MEDICAL DEVICE AND METHOD FOR MAKING THE SAME NOVARTIS AG (CH) 2004-03-25 WO claimed
CN-1283280-A Actively controllable multifocal lens NOVARTIS AG (CH) 2001-02-07 CN claimed
EP-1044389-A2 ACTIVELY CONTROLLABLE MULTIFOCAL LENS Novartis AG (CH) 2000-10-18 EP claimed
US-5997140-A Actively controllable multifocal lens NOVARTIS AG (CH) 1999-12-07 US claimed
WO-1999034239-A2 ACTIVELY CONTROLLABLE MULTIFOCAL LENS NOVARTIS AG (CH) 1999-07-08 WO claimed
US-4123408-A Hydrogel contact lens AMERICAN OPTICAL CORPORATION (US) 1978-10-31 US claimed
US-4123407-A Hydrophilic contact lens AMERICAN OPTICAL CORPORATION (US) 1978-10-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA GRM5 4205/4885PKM 3590/4885
US-12595368-B2 UV/HEVL-filtering contact lenses UACA, HSPA4L, RAD54L GRM5 2926/4885PKM 2225/4885
US-12570784-B2 Method for making embedded hydrogel contact lenses CRYAB, CRYZ, CRYAA GRM5 4056/4885PKM 2661/4885
US-12638614-B2 Method for making silicone hydrogel contact lenses SMCHD1, CRYAA, CRYZ GRM5 838/4885PKM 2917/4885
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES CRYZ, CRYAB, CRYAA GRM5 3693/4885PKM 2895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.