Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20269292 | 0.85 | KMT2A (0.45) | TSHRL3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL4236408 | 0.83 | L3MBTL1 (0.50) | TSHRL3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL4233008 | 0.83 | ALDH1A1 (0.43) | TSHRL3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL6002417 | 0.80 | TSHR (0.47) | TSHRL3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL6002421 | 0.80 | KMT2A (0.49) | TSHRL3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL1532507 | 0.79 | ALDH1A1 (0.47) | TSHRL3MBTL1TDP1KMT2AMEN1 | |
| SCHEMBL5535025 | 0.76 | ALDH1A1 (0.48) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL15896735 | 0.76 | TSHR (0.54) | TSHRL3MBTL1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13156984 | 0.76 | TSHR (0.54) | TSHRL3MBTL1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11808202 | 0.76 | TSHR (0.54) | TSHRL3MBTL1TDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060292188-A1 | Ophthalmic solution with a flavoring agent | BAUSCH & LOMB INCORPORATED | 2006-12-28 | — | — | US | claimed |
| WO-2006132870-A1 | OPHTHALMIC SOLUTION WITH A FLAVORING AGENT | BAUSCH & LOMB INCORPORATED (US) | 2006-12-14 | — | — | WO | claimed |
| US-9701177-B2 | Ceramic coated automotive heat exchanger components | HENKEL AG & CO. KGAA (DE) | 2017-07-11 | — | — | US | disclosed |
| US-20130137625-A1 | Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof | SOLARBRE, INC. (US) | 2013-05-30 | — | — | US | disclosed |
| US-8246869-B2 | Photo-responsive microencapsulation materials, compositions and methods of use thereof | SOLARBRE, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| EP-2414764-A2 | CERAMIC COATED AUTOMOTIVE HEAT EXCHANGER COMPONENTS | Henkel AG & Co. KGaA (DE) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010114988-A2 | CERAMIC COATED AUTOMOTIVE HEAT EXCHANGER COMPONENTS | HENKEL AG & CO. KGAA (DE) | 2010-10-07 | — | — | WO | disclosed |
| US-20100252241-A1 | CERAMIC COATED AUTOMOTIVE HEAT EXCHANGER COMPONENTS | HENKEL AG & CO. KGAA (DE) | 2010-10-07 | — | — | US | disclosed |
| US-20090202652-A1 | Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof | SOLARBRE, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| EP-1945344-A2 | PHOTO-RESPONSIVE MICROENCAPSULATION MATERIALS, COMPOSITIONS AND METHODS OF USE THEREOF | Solarbre, Inc. (US) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007051198-A2 | PHOTO-RESPONSIVE MICROENCAPSULATION MATERIALS, COMPOSITIONS AND METHODS OF USE THEREOF | SOLARBRE, INC (US) | 2007-05-03 | — | — | WO | disclosed |
| US-20070014992-A1 | Scented multilayer films and method of making | LONGMOORE KENNETH J | 2007-01-18 | — | — | US | disclosed |
| US-20070014993-A1 | Scented multilayer films and method of making | APPLIED EXTRUSION TECHNOLOGIES, INC. | 2007-01-18 | — | — | US | disclosed |
| US-20060292188-A1 | Ophthalmic solution with a flavoring agent | BAUSCH & LOMB INCORPORATED | 2006-12-28 | — | — | US | disclosed |
| US-20060292189-A1 | Ophthalmic solution with a flavoring agent as a dosing indicator and method for indicating dosage of an ophthalmic solution | BAUSCH & LOMB INCORPORATED | 2006-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090202652-A1 | Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof | LIPA, LIPE, CRYAA | TSHR 4608/4885L3MBTL1 3746/4885TDP1 3305/4885 |
| US-20060292188-A1 | Ophthalmic solution with a flavoring agent | TAS2R60, TAS2R10, TAS2R40 | TSHR 1000/4885L3MBTL1 4714/4885TDP1 4272/4885 |
| US-20060292189-A1 | Ophthalmic solution with a flavoring agent as a dosing indicator and method for indicating dosage of an ophthalmic solution | TAS2R7, TAS2R40, TAS2R42 | TSHR 984/4885L3MBTL1 4708/4885TDP1 2387/4885 |
| US-20130137625-A1 | Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof | LIPA, LIPE, CRYAA | TSHR 4608/4885L3MBTL1 3746/4885TDP1 3305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.