Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265567 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2TSHRMAPTMEN1KMT2A | |
| SCHEMBL8224624 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2TSHRMAPTMEN1KMT2A | |
| SCHEMBL6718014 | 0.90 | SMN1; SMN2 (0.54) | SMN1; SMN2TSHRMAPTMEN1KMT2A | |
| SCHEMBL15587121 | 0.90 | SMN1; SMN2 (0.54) | SMN1; SMN2TSHRMAPTMEN1KMT2A | |
| SCHEMBL15587059 | 0.90 | SMN1; SMN2 (0.54) | SMN1; SMN2TSHRMAPTMEN1KMT2A | |
| Phosphine SCHEMBL27419558 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRMAPTMEN1KMT2A | |
| SCHEMBL28578770 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRMAPTMEN1KMT2A | |
| SCHEMBL28329152 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRMAPTMEN1KMT2A | |
| SCHEMBL29232860 | 0.86 | TSHR (0.58) | SMN1; SMN2TSHRMEN1KMT2ANPC1 | |
| SCHEMBL29006983 | 0.86 | TSHR (0.58) | SMN1; SMN2TSHRMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118217-A1 | Agonists for Antimicrobial Peptide Systems | AKTHELIA PHARMACEUTICALS (IS) | 2011-05-19 | — | — | US | claimed |
| EP-2237684-A2 | AGONISTS FOR ANTIMICROBIAL PEPTIDE SYSTEMS | Akthelia Pharmaceuticals (IS) | 2010-10-13 | — | — | EP | claimed |
| WO-2009087474-A2 | AGONISTS FOR ANTIMICROBIAL PEPTIDE SYSTEMS | AKTHELIA PHARMACEUTICALS (IS) | 2009-07-16 | — | — | WO | claimed |
| US-20060292188-A1 | Ophthalmic solution with a flavoring agent | BAUSCH & LOMB INCORPORATED | 2006-12-28 | — | — | US | claimed |
| WO-2006132870-A1 | OPHTHALMIC SOLUTION WITH A FLAVORING AGENT | BAUSCH & LOMB INCORPORATED (US) | 2006-12-14 | — | — | WO | claimed |
| EP-2649033-B1 | COMPOSITIONS AND METHODS FOR STABILIZING INGREDIENTS USING 2,4-PENTANEDIONE COMPOUNDS | SYTHEON LTD (US) | 2018-10-17 | — | — | EP | disclosed |
| EP-3356356-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |
| US-9701177-B2 | Ceramic coated automotive heat exchanger components | HENKEL AG & CO. KGAA (DE) | 2017-07-11 | — | — | US | disclosed |
| US-20150258047-A1 | Therapeutic Compounds | AKTHELIA PHARMACEUTICALS (IS) | 2015-09-17 | — | — | US | disclosed |
| US-9078864-B2 | Agonists for antimicrobial peptide systems | AKTHELIA PHARMACEUTICALS (IS) | 2015-07-14 | — | — | US | disclosed |
| CN-101959429-B | Agonists of antimicrobial peptide systems | AKTHELIA PHARMACEUTICALS | 2014-09-10 | — | — | CN | disclosed |
| US-20140155358-A1 | Therapeutic Compounds | AKTHELIA PHARMACEUTICALS (IS) | 2014-06-05 | — | — | US | disclosed |
| US-20080131381-A1 | METHODS FOR PHOTOSTABILIZING INGREDIENTS WITHIN COSMETICS, PERSONAL CARE AND HOUSEHOLD PRODUCTS AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GESELLSCHAFT (DE) | 2008-06-05 | — | — | US | disclosed |
| US-20070014993-A1 | Scented multilayer films and method of making | APPLIED EXTRUSION TECHNOLOGIES, INC. | 2007-01-18 | — | — | US | disclosed |
| US-20070014992-A1 | Scented multilayer films and method of making | LONGMOORE KENNETH J | 2007-01-18 | — | — | US | disclosed |
| US-20060292189-A1 | Ophthalmic solution with a flavoring agent as a dosing indicator and method for indicating dosage of an ophthalmic solution | BAUSCH & LOMB INCORPORATED | 2006-12-28 | — | — | US | disclosed |
| US-20060292188-A1 | Ophthalmic solution with a flavoring agent | BAUSCH & LOMB INCORPORATED | 2006-12-28 | — | — | US | disclosed |
| US-7150876-B2 | Methods for stabilizing ingredients within cosmetics, personal care and household products | MERCK PATENT GMBH (DE) | 2006-12-19 | — | — | US | disclosed |
| US-20050244349-A1 | Methods for stabilizing ingredients within cosmetics, personal care and household products | SUSONITY Commercial GmbH (DE) | 2005-11-03 | — | — | US | disclosed |
| EP-1591099-A2 | Methods for stabilizing ingredients within cosmetics, personal care and household products | MERCK PATENT GmbH (DE) | 2005-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060292188-A1 | Ophthalmic solution with a flavoring agent | TAS2R60, TAS2R10, TAS2R40 | SMN1; SMN2 820/4885TSHR 1000/4885MAPT 678/4885 |
| US-20060292189-A1 | Ophthalmic solution with a flavoring agent as a dosing indicator and method for indicating dosage of an ophthalmic solution | TAS2R7, TAS2R40, TAS2R42 | SMN1; SMN2 573/4885TSHR 984/4885MAPT 1498/4885 |
| US-20110118217-A1 | Agonists for Antimicrobial Peptide Systems | VIP, GLP1R, MAVS | SMN1; SMN2 3320/4885TSHR 2225/4885MAPT 4030/4885 |
| US-20050244349-A1 | Methods for stabilizing ingredients within cosmetics, personal care and household products | CUTA, TYR, LAGE3 | SMN1; SMN2 1823/4885TSHR 4198/4885MAPT 328/4885 |
| US-20150258047-A1 | Therapeutic Compounds | VIP, CFTR, ATF1 | SMN1; SMN2 3945/4885TSHR 943/4885MAPT 900/4885 |
| US-20140155358-A1 | Therapeutic Compounds | VIP, CFTR, GABBR1 | SMN1; SMN2 3869/4885TSHR 1406/4885MAPT 908/4885 |
| US-20080131381-A1 | METHODS FOR PHOTOSTABILIZING INGREDIENTS WITHIN COSMETICS, PERSONAL CARE AND HOUSEHOLD PRODUCTS AND COMPOSITIONS OBTAINED THEREFROM | TYR, NISCH, PPOX | SMN1; SMN2 3270/4885TSHR 4214/4885MAPT 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.