Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5399852 | 1.00 | HDAC8 (0.55) | HDAC8HDAC6SMN1; SMN2MAPTMTNR1A | |
| SCHEMBL5474591 | 0.85 | LMNA (0.53) | MAPTMAPK1NPC1KDM4ERAB9A | |
| SCHEMBL5474595 | 0.85 | LMNA (0.53) | MAPTMAPK1NPC1KDM4ERAB9A | |
| SCHEMBL29788409 | 0.83 | LMNA (0.38) | HDAC8HDAC6SMN1; SMN2MAPTMTNR1A | |
| SCHEMBL2846706 | 0.83 | CYP11B2 (0.42) | HDAC8HDAC6SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2846708 | 0.83 | CYP11B2 (0.42) | HDAC8HDAC6SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5292811 | 0.83 | HDAC8 (0.64) | HDAC8HDAC6SMN1; SMN2MAPTMTNR1A | |
| SCHEMBL17159071 | 0.82 | LMNA (0.40) | HDAC8HDAC6SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL17159068 | 0.82 | LMNA (0.40) | HDAC8HDAC6SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL25068370 | 0.80 | HDAC8 (0.59) | HDAC8HDAC6SMN1; SMN2MAPTMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291752-B2 | Production method of β-amino acid | AJINOMOTO CO., INC. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040210064-A1 | Production method of beta-amino acid | AJINOMOTO CO., INC. (JP) | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040210064-A1 | Production method of beta-amino acid | BCAT2, BCAT1, AADAT | HDAC8 3676/4885HDAC6 2996/4885SMN1; SMN2 3609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.