SCHEMBL540087

SCHEMBL540087

Cc1cccc(OP(=O)(O)O)c1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.58
LMNA P02545 3/20 0.53
INPPL1 O15357 3/20 0.52
INPP5A Q14642 3/20 0.52
ACHE P22303 1/20 0.52
MAPT P10636 1/20 0.51
HTT P42858 1/20 0.51
L3MBTL1 Q9Y468 3/20 0.48
TDP1 Q9NUW8 1/20 0.48
NPSR1 Q6W5P4 2/20 0.47
GAA P10253 1/20 0.47
MAPK1 P28482 1/20 0.46
KMT2A Q03164 2/20 0.45
INPP5B P32019 1/20 0.44
MEN1 O00255 1/20 0.44
ACP3 P15309 1/20 0.43
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31169481 1.00 SRC (0.58) SRCLMNAINPPL1INPP5AACHE
Hydrochloric Acid SCHEMBL11751642 0.98 SRC (0.56) SRCLMNAINPPL1INPP5AACHE
SCHEMBL3388030 0.88 LMNA (0.53) SRCLMNAACHEMAPTHTT
SCHEMBL30529849 0.88 LMNA (0.53) SRCLMNAACHEMAPTHTT
SCHEMBL29758988 0.88 LMNA (0.53) SRCLMNAACHEMAPTHTT
SCHEMBL130697 0.85 INPPL1 (0.71) SRCINPPL1INPP5AKMT2AINPP5B
SCHEMBL10838769 0.85 LMNA (0.50) SRCLMNAACHEMAPTHTT
SCHEMBL187081 0.83 ALDH1A1 (0.61) LMNAACHEMAPTHTTL3MBTL1
SCHEMBL29790831 0.83 ALDH1A1 (0.61) LMNAACHEMAPTHTTL3MBTL1
Phosphoric Acid SCHEMBL28992406 0.83 INPPL1 (0.68) SRCINPPL1INPP5AKMT2AINPP5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008091135-A1 CONDUCTIVE POLYMER COMPOSITION FOR RADIOGRAPHIC IMAGING ELPANI CO., LTD. (KR) 2008-07-31 WO claimed
CN-116745025-A membrane for water filtration 水通道蛋白有限公司 2023-09-12 CN disclosed
CN-112930383-B Composition, film, laminated structure, light-emitting device, and display 住友化学株式会社 2023-09-08 CN disclosed
CN-113583042-B Preparation method of phosphoryl fluoride compound 烟台大学 2023-08-29 CN disclosed
CN-111655818-B Composition, film, laminate structure, light emitting device, and display 住友化学株式会社 2023-05-09 CN disclosed
CN-113583042-A Preparation method of phosphoryl fluoride compound 烟台大学 2021-11-02 CN disclosed
WO-2021113686-A1 MASP-2 INHIBITORS AND METHODS OF USE OMEROS CORPORATION (US) 2021-06-10 WO disclosed
WO-2019112930-A1 ADHESIVE COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2019-06-13 WO disclosed
US-9920083-B2 Image recording paper medium and image recording method FUJIFILM CORPORATION (JP) 2018-03-20 US disclosed
US-20160250866-A1 IMAGE RECORDING PAPER MEDIUM AND IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2016-09-01 US disclosed
US-20150191490-A1 MITOTIC KINESIN INHIBTORS AND METHODS OF USE THEREOF ARRAY BIOPHARMA INC. (US) 2015-07-09 US disclosed
US-8580828-B2 Mitotic kinesin inhibitors and methods of use thereof ARRAY BIOPHARMA INC. (US) 2013-11-12 US disclosed
US-20130109656-A1 MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF ARRAY BIOPHARMA, INC. 2013-05-02 US disclosed
US-8389638-B2 Multifunctional additive grafted rubber and process for the preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2013-03-05 US disclosed
EP-2168781-B1 Heat-sensitive transfer sheet FUJIFILM CORP (JP) 2012-02-08 EP disclosed
US-20090062474-A1 NOVEL MULTIFUNCTIONAL ADDITIVE GRAFTED RUBBER AND PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2009-03-05 US disclosed
WO-2008091135-A1 CONDUCTIVE POLYMER COMPOSITION FOR RADIOGRAPHIC IMAGING ELPANI CO., LTD. (KR) 2008-07-31 WO disclosed
US-5679763-A Polyquinoline-based nonlinear optical materials ENICHEM S.P.A. (IT) 1997-10-21 US disclosed
EP-0729056-A1 Polyquinoline-based nonlinear optical materials ENICHEM S.p.A. (IT) 1996-08-28 EP disclosed
WO-1995012628-A1 CONJUGATED POLYMER EXCIPLEXES AND APPLICATIONS THEREOF RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1995-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130109656-A1 MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF KIF5B, KIF2C, KIFC1 SRC 2473/4885LMNA 1583/4885INPPL1 862/4885
US-20150191490-A1 MITOTIC KINESIN INHIBTORS AND METHODS OF USE THEREOF KIF5B, KIF2C, KIFC1 SRC 2999/4885LMNA 1419/4885INPPL1 986/4885
US-20160250866-A1 IMAGE RECORDING PAPER MEDIUM AND IMAGE RECORDING METHOD PHOSPHO1, ITPR2, PPIP5K2 SRC 636/4885LMNA 3055/4885INPPL1 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.