Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2299170 | 0.80 | TRPM8 (0.48) | TRPM8ALDH1A1MAPTRAB9AL3MBTL1 | |
| SCHEMBL5420760 | 0.79 | P4HB (0.37) | HPGDGAAHDAC1LMNA | |
| SCHEMBL5411600 | 0.77 | TRPM8 (0.41) | TRPM8ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL22263615 | 0.76 | TRPM8 (0.54) | TRPM8ALDH1A1MAPTRAB9AHPGD | |
| SCHEMBL9446229 | 0.76 | TRPM8 (0.48) | TRPM8ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL6031703 | 0.76 | TRPM8 (0.48) | TRPM8ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL9446234 | 0.76 | TRPM8 (0.48) | TRPM8ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL5416084 | 0.76 | NFE2L2 (0.48) | ALDH1A1MAPTMAPK1RAB9AL3MBTL1 | |
| SCHEMBL5414303 | 0.76 | NFE2L2 (0.48) | ALDH1A1MAPTMAPK1RAB9AL3MBTL1 | |
| SCHEMBL5415538 | 0.75 | RELA (0.43) | ALDH1A1MAPTMAPK1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7311860-B2 | 1,3,5-tricyano-2,4,6-tris(vinyl)benzene derivatives and method for preparing the same | KOREA UNIVERSITY FOUNDATION (KR) | 2007-12-25 | — | — | US | disclosed |
| US-20040251452-A1 | 1,3,5-Tricyano-2,4,6-tris(vinyl)benzene derivatives and method for preparing the same | SFC CO., LTD. (KR) | 2004-12-16 | — | — | US | disclosed |
| WO-2003011817-A1 | 1, 3, 5-TRICYANO-2, 4, 6-TRIS(VINYL)BENZENE DERIVATIVES AND METHOD FOR PREPARING THE SAME | KOREA UNIVERSITY FOUNDATION (KR) | 2003-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040251452-A1 | 1,3,5-Tricyano-2,4,6-tris(vinyl)benzene derivatives and method for preparing the same | TDO2, TRPV6, TRPC6 | TRPM8 171/4885ALDH1A1 1357/4885MAPT 899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.