Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5229259 | 0.91 | NR1H2 (0.43) | NR1H2CSF1RKDRSIGMAR1L3MBTL1 | |
| SCHEMBL5233887 | 0.84 | HTR6 (0.41) | SIGMAR1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL5228985 | 0.78 | MAOA (0.35) | SIGMAR1BCHEACHE | |
| SCHEMBL5233411 | 0.77 | G6PD (0.40) | L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL5421563 | 0.74 | SIGMAR1 (0.38) | CSF1RKDRSIGMAR1L3MBTL1KMT2A | |
| SCHEMBL5226141 | 0.68 | SIGMAR1 (0.39) | SIGMAR1BCHEACHE | |
| SCHEMBL30619908 | 0.62 | NR1H2 (0.50) | NR1H2 | |
| SCHEMBL5231971 | 0.61 | ALDH1A1 (0.34) | SIGMAR1KMT2AALDH1A1HPGD | |
| SCHEMBL5226351 | 0.59 | MPO (0.40) | DYRK1A | |
| SCHEMBL27165276 | 0.59 | TOP2A (0.52) | SIGMAR1L3MBTL1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312213-B2 | Substituted benzo[e][1,4]oxazino[3,2-g]isoindole compounds | LES LABORATORIES SERVIER (FR) | 2007-12-25 | — | — | US | disclosed |
| US-20060003997-A1 | Substituted benzo[e] [1,4] oxazino [3,2-g] isoindole compounds | LES LABORATOIRES SERVIER (FR) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060003997-A1 | Substituted benzo[e] [1,4] oxazino [3,2-g] isoindole compounds | H1-3, H1-0, H1-2 | NR1H2 483/4885CA12 1887/4885CA1 3428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.