Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL545383 | 1.00 | OPRM1 (0.46) | OPRM1TRPV1FAAHERN1TNNC1 | |
| SCHEMBL28995072 | 0.93 | OPRM1 (0.46) | OPRM1TRPV1FAAHTNNC1 | |
| SCHEMBL13562266 | 0.84 | APP (0.48) | OPRM1TNNC1 | |
| SCHEMBL29199916 | 0.82 | PDE5A (0.43) | OPRM1TRPV1TNNC1 | |
| SCHEMBL3901500 | 0.79 | OPRM1 (0.47) | OPRM1TRPV1FAAHERN1 | |
| SCHEMBL3901498 | 0.79 | OPRM1 (0.47) | OPRM1TRPV1FAAHERN1 | |
| SCHEMBL17938807 | 0.78 | PTGS2 (0.48) | TNNC1 | |
| SCHEMBL2370035 | 0.78 | PTGS2 (0.48) | TNNC1 | |
| SCHEMBL11296041 | 0.78 | PTGS2 (0.48) | TNNC1 | |
| SCHEMBL11296037 | 0.78 | PTGS2 (0.48) | TNNC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130081999-A1 | Bridged Macrocyclic Module Compositions | WHITEFORD JEFFERY A (US) | 2013-04-04 | — | — | US | disclosed |
| US-8182695-B2 | Bridged macrocyclic module compositions | WHITEFORD JEFFERY A (US) | 2012-05-22 | — | — | US | disclosed |
| US-8110679-B2 | Nanofilm and membrane compositions | COVALENT PARTNERS LLC (US) | 2012-02-07 | — | — | US | disclosed |
| US-7767810-B2 | Macrocyclic modules comprising linked cyclic synthon units for use in the formation of selectively permeable membranes | COVALENT PARTNERS, LLC (US) | 2010-08-03 | — | — | US | disclosed |
| US-20100152438-A1 | AMPHIPHILIC MOLECULAR MODULES AND CONSTRUCTS BASED THEREON | COVALENT PARTNERS LLC | 2010-06-17 | — | — | US | disclosed |
| US-7595368-B2 | Nanofilm compositions with polymeric components | COVALENT PARTNERS, LLC (US) | 2009-09-29 | — | — | US | disclosed |
| US-7563890-B2 | Amphiphilic molecular modules and constructs based thereon | COVALENT PARTNERS, LLC (US) | 2009-07-21 | — | — | US | disclosed |
| US-20090114596-A1 | NANOFILM AND MEMBRANE COMPOSITIONS | COVALENT PARTNERS LLC | 2009-05-07 | — | — | US | disclosed |
| US-20080290034-A1 | Bridged macrocyclic module compositions | COVALENT PARTNERS LLC | 2008-11-27 | — | — | US | disclosed |
| US-7432371-B2 | Nanofilm and membrane compositions | COVALENT PARTNERS, LLC (US) | 2008-10-07 | — | — | US | disclosed |
| WO-2005030711-A2 | BRIDGED MACROCYCLIC MODULE COMPOSITIONS | COVALENT PARTNERS LLC (US) | 2005-04-07 | — | — | WO | disclosed |
| WO-2005018013-A2 | NANOFILM COMPOSITIONS WITH POLYMERIC COMPONENTS | COVALENT PARTNERS, LLC (US) | 2005-02-24 | — | — | WO | disclosed |
| US-20040260085-A1 | Nanofilm and membrane compositions | COVALENT PARTNERS LLC | 2004-12-23 | — | — | US | disclosed |
| EP-1481268-A2 | NANOFILM AND MEMBRANE COMPOSITIONS | Covalent Partners, LLC (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1480635-A2 | MACROCYCLIC MODULE COMPOSITIONS | Covalent Partners, LLC (US) | 2004-12-01 | — | — | EP | disclosed |
| US-20040106741-A1 | Nanofilm compositions with polymeric components | COVALENT PARTNERS LLC | 2004-06-03 | — | — | US | disclosed |
| US-20040034223-A1 | Amphiphilic molecular modules and constructs based thereon | COVALENT PARTNERS, LLC. | 2004-02-19 | — | — | US | disclosed |
| US-20030199688-A1 | Macrocyclic module compositions | COVALENT PARTNERS, LLC | 2003-10-23 | — | — | US | disclosed |
| WO-2003067286-A2 | NANOFILM AND MEMBRANE COMPOSITIONS | COVALENT PARTNERS, LLC (US) | 2003-08-14 | — | — | WO | disclosed |
| WO-2003066646-A2 | MACROCYCLIC MODULE COMPOSITIONS | COVALENT PARTNERS, LLC (US) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199688-A1 | Macrocyclic module compositions | CYCS, IMMT, INTS9 | OPRM1 3731/4885TRPV1 1485/4885FAAH 2846/4885 |
| US-20100152438-A1 | AMPHIPHILIC MOLECULAR MODULES AND CONSTRUCTS BASED THEREON | ANXA6, THEM6, ANXA5 | OPRM1 3808/4885TRPV1 692/4885FAAH 1060/4885 |
| US-20040034223-A1 | Amphiphilic molecular modules and constructs based thereon | ANXA6, THEM6, ANXA5 | OPRM1 3808/4885TRPV1 692/4885FAAH 1060/4885 |
| US-20040260085-A1 | Nanofilm and membrane compositions | CLPTM1, APMAP, PHOSPHO1 | OPRM1 118/4885TRPV1 1888/4885FAAH 3694/4885 |
| US-20130081999-A1 | Bridged Macrocyclic Module Compositions | SBDS, NCL, INTS6 | OPRM1 1546/4885TRPV1 3166/4885FAAH 3818/4885 |
| US-20080290034-A1 | Bridged macrocyclic module compositions | SBDS, NCL, INTS6 | OPRM1 1658/4885TRPV1 3283/4885FAAH 3958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.