Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3219206 | 0.76 | SIGMAR1 (0.47) | SIGMAR1PTGIRDRD2L3MBTL1MEN1 | |
| SCHEMBL29888725 | 0.74 | RAB9A (0.43) | L3MBTL1KDM4ESMN1; SMN2POLBNPC1 | |
| SCHEMBL28127913 | 0.70 | HPGDS (0.38) | SIGMAR1PTGIRABCB1ABCC1ABCG2 | |
| SCHEMBL28127932 | 0.67 | HCRTR1 (0.33) | MEN1KMT2APOLBHTT | |
| Hydrochloric Acid SCHEMBL28127907 | 0.67 | KMT2A (0.38) | SIGMAR1DRD2KCNH2ABCB1ABCC1 | |
| SCHEMBL30586343 | 0.66 | SIGMAR1 (0.47) | SIGMAR1L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL5423323 | 0.64 | MMP13 (0.55) | L3MBTL1MEN1KMT2AQPCTKDM4E | |
| SCHEMBL28128186 | 0.64 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL16466563 | 0.64 | PTGIR (0.40) | SIGMAR1PTGIRL3MBTL1MEN1KMT2A | |
| SCHEMBL16466374 | 0.64 | PTGIR (0.40) | SIGMAR1PTGIRL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270589-A1 | Quinazoline Derivative and Process for Producing the Same | MITSUBISHI PHARMA CORPORATION (JP) | 2007-11-22 | — | — | US | disclosed |
| EP-1690856-A1 | QUINAZOLINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | Mitsubishi Pharma Corporation (JP) | 2006-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270589-A1 | Quinazoline Derivative and Process for Producing the Same | TP53, NQO2, AQP1 | SIGMAR1 2992/4885PTGIR 2893/4885DHFR 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.