Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462225 | 0.91 | MMP2 (0.39) | SCN7AKCNH2SCN9ALMNAMAPK1 | |
| SCHEMBL5324832 | 0.84 | HPGD (0.34) | — | |
| SCHEMBL5317625 | 0.83 | MMP1 (0.34) | MAPK1SMN1; SMN2 | |
| SCHEMBL5322497 | 0.81 | SLC6A2 (0.36) | SMN1; SMN2 | |
| SCHEMBL5395845 | 0.81 | MMP1 (0.35) | MAPK1SMN1; SMN2 | |
| SCHEMBL3868068 | 0.79 | MMP2 (0.42) | — | |
| SCHEMBL5319325 | 0.79 | CCR1 (0.34) | — | |
| SCHEMBL5372203 | 0.78 | GPR183 (0.35) | KCNH2SMN1; SMN2 | |
| SCHEMBL5316333 | 0.78 | ADAM17 (0.38) | LMNAMAPK1HTT | |
| SCHEMBL5368861 | 0.78 | CETP (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010751-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-02-02 | — | — | WO | disclosed |