Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 5/20 | 0.35 |
| ▸ | PDE2A | O00408 | 3/20 | 0.34 |
| ▸ | CFTR | P13569 | 6/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379472 | 0.91 | MMP1 (0.39) | GPR183PDE2ACFTRHTR2APDE4D | |
| SCHEMBL5419543 | 0.88 | ALDH1A1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL5489951 | 0.83 | TAS1R3 (0.36) | P2RX3 | |
| SCHEMBL5384481 | 0.82 | TAS1R3 (0.34) | — | |
| SCHEMBL5316333 | 0.81 | ADAM17 (0.38) | HTR2AKDM4EALDH1A1RECQL | |
| SCHEMBL5317625 | 0.81 | MMP1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5324832 | 0.80 | HPGD (0.34) | ALDH1A1 | |
| SCHEMBL5322497 | 0.79 | SLC6A2 (0.36) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5318347 | 0.79 | ALDH1A1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL5341776 | 0.78 | MMP1 (0.40) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-11 | — | — | EP | claimed |
| WO-2006010751-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-02-02 | — | — | WO | claimed |