Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | TDP2 | O95551 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 4/20 | 0.54 |
| ▸ | BCR | P11274 | 4/20 | 0.54 |
| ▸ | PRKCA | P17252 | 4/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | PRKCG | P05129 | 1/20 | 0.53 |
| ▸ | PRKCB | P05771 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5470733 | 0.87 | MEN1 (0.56) | PLK1TDP2KMT2AMEN1MAPT | |
| SCHEMBL5471802 | 0.83 | RAB9A (0.60) | PLK1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL5470852 | 0.83 | ADORA1 (0.69) | MAPTABL1BCRPRKCASRC | |
| SCHEMBL5477050 | 0.82 | PLK1 (0.56) | PLK1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL5462697 | 0.81 | ALDH1A1 (0.58) | TDP2ALDH1A1ABL1BCRPRKCA | |
| SCHEMBL5470769 | 0.79 | PLK1 (0.53) | PLK1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL5465350 | 0.78 | SIRT2 (0.68) | ABL1BCRPRKCASRCPRKD3 | |
| SCHEMBL5466956 | 0.78 | JAK2 (0.72) | PLK1KMT2AALDH1A1MAPTABL1 | |
| SCHEMBL5465537 | 0.78 | KMO (0.61) | ALDH1A1MAPTABL1BCRPRKCA | |
| SCHEMBL15688998 | 0.77 | MEN1 (0.87) | HDAC2KMT2AMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1679309-A1 | ANTISTRESS DRUG AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | PLK1 3377/4885HDAC2 1336/4885TDP2 2886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.