Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.58 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.52 |
| ▸ | PRKCA | P17252 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5472976 | 0.91 | PIK3CA (0.59) | PIK3CAHDAC2JAK2KDM4EMAPT | |
| SCHEMBL5465350 | 0.88 | SIRT2 (0.68) | SIRT2PRKCAJAK2DYRK1AADORA1 | |
| SCHEMBL5465855 | 0.85 | HDAC1 (0.67) | PIK3CAPRKCAJAK2HDAC1DYRK1A | |
| SCHEMBL5459991 | 0.83 | PRKCA (0.52) | PIK3CAHDAC2HDAC3NCOR1PRKCA | |
| SCHEMBL5465964 | 0.83 | RAB9A (0.60) | PIK3CAKDM4EMAPTABL1PDGFRB | |
| SCHEMBL2178971 | 0.81 | HDAC2 (0.48) | PIK3CAHDAC2HDAC3NCOR1PRKCA | |
| SCHEMBL5470852 | 0.80 | ADORA1 (0.69) | PRKCAJAK2HDAC1KDM4EMAPT | |
| SCHEMBL5473232 | 0.79 | DYRK1A (0.63) | PRKCAJAK2DYRK1AMAPTADORA3 | |
| SCHEMBL5462749 | 0.78 | SCN10A (0.54) | PIK3CAJAK2ADORA1ABL1 | |
| SCHEMBL5472823 | 0.77 | ADORA1 (0.57) | HDAC2PRKCAJAK2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1679309-A1 | ANTISTRESS DRUG AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | PIK3CA 4595/4885HSD17B1 343/4885HSD17B2 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.