Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.67 |
| ▸ | PRKCA | P17252 | 1/20 | 0.59 |
| ▸ | CAMKK2 | Q96RR4 | 4/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.59 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.55 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | BCR | P11274 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | TDO2 | P48775 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.51 |
| ▸ | GAK | O14976 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5465449 | 0.85 | PIK3CA (0.58) | HDAC1PRKCAPIK3CGABL1BCR | |
| SCHEMBL5472976 | 0.84 | PIK3CA (0.59) | CAMKK2PIK3CGMAPK8JAK2PIK3CA | |
| SCHEMBL5465340 | 0.82 | ALDH1A1 (0.61) | HDAC1CAMKK2PIK3CGMAPK8ABL1 | |
| SCHEMBL5465150 | 0.82 | HDAC1 (0.58) | HDAC1CAMKK2PIK3CGMAPK8AGTR1 | |
| SCHEMBL5459991 | 0.82 | PRKCA (0.52) | HDAC1PRKCACAMKK2PIK3CGABL1 | |
| SCHEMBL5465350 | 0.82 | SIRT2 (0.68) | PRKCAABL1BCRJAK2DYRK1A | |
| SCHEMBL5470852 | 0.81 | ADORA1 (0.69) | HDAC1PRKCACAMKK2PIK3CGMAPK8 | |
| SCHEMBL1064494 | 0.81 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL5473232 | 0.80 | DYRK1A (0.63) | PRKCACAMKK2MAPK8ABL1BCR | |
| SCHEMBL4903189 | 0.80 | PIK3CG (0.61) | PRKCACAMKK2PIK3CGMAPK8ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | HDAC1 1358/4885PRKCA 4186/4885CAMKK2 2459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.