Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084909 | 0.77 | TRPV4 (0.57) | CYP11B1CYP11B2ALDH1A1KDM4EUSP2 | |
| SCHEMBL1156401 | 0.77 | TRPV4 (0.57) | CYP11B1CYP11B2ALDH1A1KDM4EUSP2 | |
| SCHEMBL30084906 | 0.77 | TRPV4 (0.57) | CYP11B1CYP11B2ALDH1A1KDM4EUSP2 | |
| SCHEMBL15148277 | 0.77 | CYP11B1 (0.35) | CYP11B1CYP11B2ALDH1A1KDM4EUSP2 | |
| SCHEMBL7292435 | 0.76 | CASP1 (0.42) | ALDH1A1KDM4EUSP2MAPTMAPK1 | |
| SCHEMBL96914 | 0.76 | CES2 (0.43) | CYP11B1CYP11B2ALDH1A1TDP1TRPV4 | |
| Methane SCHEMBL27650148 | 0.76 | TRPV4 (0.55) | CYP11B1CYP11B2ALDH1A1KDM4EUSP2 | |
| Fluoride SCHEMBL21646063 | 0.76 | TRPV4 (0.55) | CYP11B1CYP11B2ALDH1A1KDM4EUSP2 | |
| SCHEMBL21201424 | 0.73 | NFE2L2 (0.36) | CYP11B1CYP11B2ALDH1A1TDP1TRPV4 | |
| SCHEMBL15540252 | 0.73 | TRPV4 (0.33) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197531-A1 | Benzoyl-piperidine derivatives as dual modulators of the 5-HT2A and D3 receptors | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197531-A1 | Benzoyl-piperidine derivatives as dual modulators of the 5-HT2A and D3 receptors | HTR2A, HTR3A, HTR2C | CYP11B1 4115/4885CYP11B2 3326/4885ALDH1A1 1315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.