Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dehydroabietic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 4/20 | 0.80 |
| ▸ | RXRA | P19793 | 1/20 | 0.80 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.80 |
| ▸ | CDK2 | P24941 | 1/20 | 0.80 |
| ▸ | RXRB | P28702 | 1/20 | 0.80 |
| ▸ | RXRG | P48443 | 1/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.61 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.61 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.61 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dehydroabietic Acid SCHEMBL7940853 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL7940620 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL7943161 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL7938545 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL7939559 | 0.98 | CYP3A4 (0.82) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL31152452 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL669758 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL669138 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL15550582 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL15744753 | 0.89 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230383245-A1 | CULTURE MEDIUM COMPOSITION | NISSAN CHEMICAL CORPORATION (JP) | 2023-11-30 | — | — | US | disclosed |
| CN-112920426-B | Rosin-based calcium salt supermolecule hydrogel, preparation method and application thereof | 华侨大学 | 2023-08-29 | — | — | CN | disclosed |
| EP-3075787-B1 | PIGMENT DISPERSION AND PRODUCING METHOD THEREOF | FUJIFILM CORP (JP) | 2023-06-07 | — | — | EP | disclosed |
| CN-112920426-A | Rosinyl calcium salt supermolecule hydrogel, and preparation method and application thereof | 华侨大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-112662611-A | Culture medium composition | 日产化学工业株式会社 | 2021-04-16 | — | — | CN | disclosed |
| CN-105934511-B | Culture medium composition | 日产化学工业株式会社 | 2021-01-22 | — | — | CN | disclosed |
| US-20200095542-A1 | CULTURE MEDIUM COMPOSITION | NISSAN CHEMICAL CORPORATION (JP) | 2020-03-26 | — | — | US | disclosed |
| US-10280329-B2 | Pigment dispersion and producing method thereof | FUJIFILM CORPORATION (JP) | 2019-05-07 | — | — | US | disclosed |
| US-20170009201-A1 | CULTURE MEDIUM COMPOSITION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-01-12 | — | — | US | disclosed |
| EP-3098300-A1 | CULTURE MEDIUM COMPOSITION | Nissan Chemical Industries, Ltd. (JP) | 2016-11-30 | — | — | EP | disclosed |
| US-20160289486-A1 | PIGMENT DISPERSION AND PRODUCING METHOD THEREOF | FUJIFILM CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |
| EP-3075787-A1 | PIGMENT DISPERSION AND PRODUCING METHOD THEREOF | FUJIFILM Corporation (JP) | 2016-10-05 | — | — | EP | disclosed |
| US-8110611-B2 | Composition for image recording, image recording ink set, and recording apparatus | FUJI XEROX CO., LTD. (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20090076219-A1 | COMPOSITION FOR IMAGE RECORDING, IMAGE RECORDING INK SET, AND RECORDING APPARATUS | FUJI XEROX CO., LTD. (JP) | 2009-03-19 | — | — | US | disclosed |
| US-6287705-B1 | ETHYLENE-PROPYLENE COPOLYMER; MULTILAYER FILM | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2001-09-11 | — | — | US | disclosed |
| US-6270911-B1 | HEAT-SEALABILITY, MOLDABILITY; FOR BAGS | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2001-08-07 | — | — | US | disclosed |
| EP-0931805-A1 | TRIBLOCK OLIGOMERS, THERMOPLASTIC RESIN COMPOSITIONS, AND ANTIFOG MOLDINGS | Mitsui Chemicals, Inc. (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0879855-A1 | THERMOPLASTIC RESIN COMPOSITION AND FILM MADE FROM THE COMPOSITION | Mitsui Chemicals, Inc. (JP) | 1998-11-25 | — | — | EP | disclosed |
| EP-0870801-A1 | ALPHA-OLEFIN/AROMATIC VINYL COPOLYMER COMPOSITION AND MOLDINGS THEREOF | Mitsui Chemicals, Inc. (JP) | 1998-10-14 | — | — | EP | disclosed |
| EP-0869146-A1 | ETHYLENE COPOLYMER COMPOSITION AND MOLDINGS | Mitsui Chemicals, Inc. (JP) | 1998-10-07 | — | — | EP | disclosed |