Dehydroabietic Acid

Dehydroabietic Acid

SCHEMBL669138

CC(C)c1ccc2c(c1)CC[C@H]1[C@@](C)(C(=O)[O-])CCC[C@]21C.[K+]

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Dehydroabietic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KARS1 Q15046 4/20 0.80
▸ RXRA P19793 1/20 0.80
▸ CCNE1 P24864 1/20 0.80
▸ CDK2 P24941 1/20 0.80
▸ RXRB P28702 1/20 0.80
▸ RXRG P48443 1/20 0.80
▸ CYP3A4 P08684 4/20 0.78
▸ LMNA P02545 1/20 0.78
▸ MEN1 O00255 3/20 0.61
▸ KMT2A Q03164 3/20 0.61
▸ TSHR P16473 2/20 0.61
▸ CYP2D6 P10635 2/20 0.61
▸ CYP2C19 P33261 2/20 0.61
▸ PDK1 Q15118 1/20 0.61
▸ PDK2 Q15119 1/20 0.61
▸ PDK3 Q15120 1/20 0.61
▸ PDK4 Q16654 1/20 0.61
▸ CYP2C9 P11712 1/20 0.61
▸ TDP1 Q9NUW8 6/20 0.60
▸ MAPK1 P28482 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dehydroabietic Acid SCHEMBL31152452 1.00 KARS1 (0.80) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL7940620 0.98 KARS1 (0.80) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL669758 0.98 KARS1 (0.80) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL7940853 0.98 KARS1 (0.80) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL7938545 0.98 KARS1 (0.80) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL15550582 0.98 KARS1 (0.80) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL7939559 0.98 CYP3A4 (0.82) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL7943161 0.98 KARS1 (0.80) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL547448 0.98 KARS1 (0.80) KARS1RXRACCNE1CDK2RXRB
Dehydroabietic Acid SCHEMBL15744753 0.89 KARS1 (1.00) KARS1RXRACCNE1CDK2RXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114230897-B High-permeability material applied to air column bag 浙江空气盒子新材料有限责任公司 2024-06-18 — — CN claimed
CN-113145086-B Fatty acid modified adsorption resin, preparation method and method for treating anionic surfactant wastewater by using same 万华化学集团股份有限公司 2022-04-22 — — CN claimed
CN-114230897-A High-permeability material applied to air column bag 杭州欧信包装科技有限公司 2022-03-25 — — CN claimed
CN-113145086-A Fatty acid modified adsorption resin, preparation method and method for treating anionic surfactant wastewater by using same 万华化学集团股份有限公司 2021-07-23 — — CN claimed
CN-106118929-A A kind of preparation method of tealeaf residue modification disproportionated rosin potassium soap 仇颖莹 2016-11-16 — — CN claimed
CN-122080337-A Copolymer of vinyl pyridine monomer, styrene monomer and acrylic ester monomer and preparation method thereof — 2026-05-26 — — CN disclosed
CN-116333833-B Preparation method of disproportionated rosin potassium soap with solid content of 80% 普洱科茂林化有限公司 2025-04-18 — — CN disclosed
EP-4308648-B1 ABS MOLDING COMPOSITION WITH IMPROVED SURFACE QUALITY FOR PLATING APPLICATIONS INEOS STYROLUTION GROUP GMBH (DE) 2024-12-25 — — EP disclosed
CN-119116506-A High-strength composite polyethylene bubble film and preparation method and application thereof 吉林三鑫工贸有限责任公司 2024-12-13 — — CN disclosed
CN-118893883-A High-strength puncture-resistant polyethylene bubble bag and preparation method thereof 吉林三鑫工贸有限责任公司 2024-11-05 — — CN disclosed
CN-116218088-B Polypropylene material and preparation method and application thereof 成都金发科技新材料有限公司 2024-10-22 — — CN disclosed
EP-4077433-B1 DUAL INITIATOR GRAFTING PROCESS OF POLYBUTADIENE LATEX BY STYRENE/ACRYLONITRILE INEOS STYROLUTION GROUP GMBH (DE) 2024-07-24 — — EP disclosed
US-5342864-A Water dispersed low molecular weight epoxy resins are advanced by coreaction with diphenol THE GLIDDEN COMPANY (US) 1994-08-30 — — US disclosed
EP-0577958-A2 Epoxide advancement process THE GLIDDEN COMPANY (US) 1994-01-12 — — EP disclosed
US-5252637-A Emulsion polymerization of epoxy resin and biphenol copolymerized with addition monomer THE GLIDDEN COMPANY (US) 1993-10-12 — — US disclosed
EP-0247346-B1 PROCESS FOR PREPARING A WATER REPELLENT CALCIUM SILICATE SHAPED PRODUCT MITSUBISHI KASEI CORPORATION (JP) 1992-07-15 — — EP disclosed
US-4775505-A REACTING CALCIUM AND SILICON COMPOUND IN PRESENCE OF SILICON OIL, MOLDING, DRYING AND STEAM CURING MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1988-10-04 — — US disclosed
EP-0247346-A2 Process for preparing a water repellent calcium silicate shaped product MITSUBISHI KASEI CORPORATION (JP) 1987-12-02 — — EP disclosed
US-4451608-A REACTION WITH ALKYLENIMINE UNION CARBIDE CORPORATION (US) 1984-05-29 — — US disclosed
US-4130523-A High solids latexes UNION CARBIDE CORPORATION (US) 1978-12-19 — — US disclosed
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