Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dehydroabietic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 known ✓ | Q15118 | 1/20 | 0.61 |
| ▸ | PDK2 known ✓ | Q15119 | 1/20 | 0.61 |
| ▸ | PDK3 known ✓ | Q15120 | 1/20 | 0.61 |
| ▸ | PDK4 known ✓ | Q16654 | 1/20 | 0.61 |
| ▸ | KARS1 | Q15046 | 4/20 | 0.80 |
| ▸ | RXRA | P19793 | 1/20 | 0.80 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.80 |
| ▸ | CDK2 | P24941 | 1/20 | 0.80 |
| ▸ | RXRB | P28702 | 1/20 | 0.80 |
| ▸ | RXRG | P48443 | 1/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dehydroabietic Acid SCHEMBL15550582 | 1.00 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL7940620 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL7943161 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL7940853 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL669138 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL31152452 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL7938545 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL547448 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL7939559 | 0.98 | CYP3A4 (0.82) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL15744753 | 0.89 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230897-B | High-permeability material applied to air column bag | 浙江空气盒子新材料有限责任公司 | 2024-06-18 | — | — | CN | claimed |
| CN-116144099-B | Thin-wall high-length-diameter-ratio polypropylene ribbon and application thereof | 张家港绿洲新材料科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-112920426-B | Rosin-based calcium salt supermolecule hydrogel, preparation method and application thereof | 华侨大学 | 2023-08-29 | — | — | CN | claimed |
| CN-116144099-A | Thin-wall high-length-diameter-ratio polypropylene ribbon and application thereof | 张家港绿洲新材料科技有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-114573911-A | Polypropylene composition suitable for thin-wall high-length-diameter ratio polypropylene ribbon and preparation method and application thereof | 张家港绿洲新材料科技有限公司 | 2022-06-03 | — | — | CN | claimed |
| CN-114230897-A | High-permeability material applied to air column bag | 杭州欧信包装科技有限公司 | 2022-03-25 | — | — | CN | claimed |
| CN-112920426-A | Rosinyl calcium salt supermolecule hydrogel, and preparation method and application thereof | 华侨大学 | 2021-06-08 | — | — | CN | claimed |
| JP-9071695-A | — | — | None | — | — | JP | disclosed |
| CN-119116506-A | High-strength composite polyethylene bubble film and preparation method and application thereof | 吉林三鑫工贸有限责任公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118893883-A | High-strength puncture-resistant polyethylene bubble bag and preparation method thereof | 吉林三鑫工贸有限责任公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-118240303-A | Polypropylene composition, preparation method of polypropylene ribbon and polypropylene ribbon prepared from polypropylene composition | 张家港绿洲新材料科技有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-114230897-B | High-permeability material applied to air column bag | 浙江空气盒子新材料有限责任公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-116144099-B | Thin-wall high-length-diameter-ratio polypropylene ribbon and application thereof | 张家港绿洲新材料科技有限公司 | 2024-04-12 | — | — | CN | disclosed |
| EP-0869146-A1 | ETHYLENE COPOLYMER COMPOSITION AND MOLDINGS | Mitsui Chemicals, Inc. (JP) | 1998-10-07 | — | — | EP | disclosed |
| JP-H0971695-A | PROPYLENE POLYMER COMPOSITION | MITSUI PETROCHEM IND LTD | 1997-03-18 | — | — | JP | disclosed |
| EP-0686663-A1 | Process for crystal nucleation of crystalline thermoplastic resin and crystalline thermoplastic resin composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-13 | — | — | EP | disclosed |
| EP-0267574-B1 | HEAT RESISTANT COPOLYMER COMPOSITION | Sumitomo Dow Limited (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-4877833-A | BLEND OF POLYMERS OF SPECIFIC COMPOSITION | SUMITOMO NAUGATUCK CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
| EP-0267574-A2 | Heat resistant copolymer composition | Sumitomo Dow Limited (JP) | 1988-05-18 | — | — | EP | disclosed |
| US-4132741-A | Process for producing haloprene | DENKA CHEMICAL CORPORATION (US) | 1979-01-02 | — | — | US | disclosed |