Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Dehydroabietic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 4/20 | 0.80 |
| ▸ | RXRA | P19793 | 1/20 | 0.80 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.80 |
| ▸ | CDK2 | P24941 | 1/20 | 0.80 |
| ▸ | RXRB | P28702 | 1/20 | 0.80 |
| ▸ | RXRG | P48443 | 1/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.61 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.61 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.61 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dehydroabietic Acid SCHEMBL669138 | 1.00 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL7940620 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL669758 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL7940853 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL7938545 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL15550582 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL7939559 | 0.98 | CYP3A4 (0.82) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL7943161 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL547448 | 0.98 | KARS1 (0.80) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL15744753 | 0.89 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119081232-A | Emulsion antioxidant and application thereof | 天津利安隆新材料股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-118923681-A | Emamectin benzoate and chlorantraniliprole dispersible oil suspending agent and preparation method thereof | 吉林金泽农药有限公司 | 2024-11-12 | — | — | CN | disclosed |