Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20505709 | 0.84 | MAP2K1 (0.38) | PDPK1 | |
| SCHEMBL29882491 | 0.84 | MAP2K1 (0.38) | PDPK1 | |
| SCHEMBL29882535 | 0.77 | GABRA1 (0.40) | — | |
| SCHEMBL18322242 | 0.77 | KDM4E (0.49) | KDM4EHPGDHSD17B10MAPTALOX15 | |
| SCHEMBL4067573 | 0.75 | GRIN1 (0.53) | DAOKDM4EHPGDHSD17B10GPR35 | |
| SCHEMBL29882774 | 0.75 | MMP2 (0.48) | KDM4EHPGDHSD17B10SRD5A2MAPT | |
| SCHEMBL24690029 | 0.74 | DAO (0.44) | DAOKDM4EHPGDHSD17B10GPR35 | |
| SCHEMBL17505244 | 0.74 | DYRK1A (0.44) | DAOKDM4EHPGDHSD17B10GPR35 | |
| SCHEMBL17505325 | 0.74 | PIN1 (0.47) | DAOKDM4EHPGDHSD17B10GPR35 | |
| SCHEMBL17505227 | 0.74 | KDM4E (0.47) | DAOKDM4EHPGDHSD17B10GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368114-A | Pyrrolopyrimidine compounds as MNK inhibitor | 生命弧度公司 | 2018-08-03 | — | — | CN | disclosed |
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | disclosed |
| CN-101056878-A | Azaindole carboxamides | SCHVARZ PHARMA AG (DE) | 2007-10-17 | — | — | CN | disclosed |
| WO-2005040073-A2 | SOLID PHASE SYNTHESIS OF 3-ARYL-2- INDOLYLCARBOXYLIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | TPH1, TPH2, HTR1A | DAO 1009/4885KDM4E 2222/4885HPGD 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.