Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6193631 | 0.83 | MEN1 (0.37) | KMT2AMEN1GAA | |
| SCHEMBL6695336 | 0.83 | ALDH1A1 (0.36) | KMT2AMEN1ALDH1A1MAPK1NPSR1 | |
| SCHEMBL6195517 | 0.83 | LMNA (0.35) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL5859331 | 0.83 | KDM4E (0.43) | KMT2AMEN1ALDH1A1OPRM1NPC1 | |
| SCHEMBL5474985 | 0.79 | KCNQ2 (0.40) | KMT2AMEN1KCNQ2ALDH1A1HIF1A | |
| SCHEMBL28080811 | 0.76 | KCNQ2 (0.47) | KMT2AMEN1KCNQ2ALDH1A1OPRM1 | |
| SCHEMBL5861434 | 0.76 | KMT2A (0.40) | KMT2AMEN1KCNQ2HIF1ANPC1 | |
| SCHEMBL6195286 | 0.75 | KMT2A (0.42) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL6193149 | 0.71 | MEN1 (0.39) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL1897977 | 0.70 | CES2 (0.36) | KMT2AMEN1KCNQ2ALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270436-A1 | NOVEL AMINO- AND IMINO-ALKYLPIPERAZINES | RECORDATI IRELAND LIMITED (IE) | 2007-11-22 | — | — | US | disclosed |
| US-20060148821-A1 | N,N-disubstituted diazocycloalkanes | RECORDATI S.A. (CH) | 2006-07-06 | — | — | US | disclosed |
| US-7071197-B2 | N,N-disubstituted diazocycloalkanes | RECORDATI S.A. (CH) | 2006-07-04 | — | — | US | disclosed |
| EP-1549627-A1 | 1-PHENYLALKYL-PIPERAZINES | Recordati Ireland Limited (IE) | 2005-07-06 | — | — | EP | disclosed |
| EP-1515961-A1 | N,N-DISUBSTITUTED DIAZOCYCLOALKANES USEFUL FOR THE TREATMENT OF CNS DISORDERS DUE TO SEROTONERGIC DYSFUNCTION | Recordati Ireland Limited (IE) | 2005-03-23 | — | — | EP | disclosed |
| US-20040072822-A1 | N,N-disubstituted diazocycloalkanes | RECORDATI S.A. (CH) | 2004-04-15 | — | — | US | disclosed |
| US-20040072839-A1 | 1-Phenylalkylpiperazines | RECORDATI S.A. (CH) | 2004-04-15 | — | — | US | disclosed |
| WO-2003106444-A1 | N,N-DISUBSTITUTED DIAZOCYCLOALKANES USEFUL FOR THE TREATMENT OF CNS DISORDERS DUE TO SEROTONERGIC DYSFUNCTION | RECORDATI S.A. (CH) | 2003-12-24 | — | — | WO | disclosed |
| WO-2003106443-A1 | 1-PHENYLALKYL-PIPERAZINES | RECORDATI S.A. (CH) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072822-A1 | N,N-disubstituted diazocycloalkanes | HTR1D, HTR1A, HTR2C | KMT2A 3664/4885MEN1 1195/4885KCNQ2 1701/4885 |
| US-20040072839-A1 | 1-Phenylalkylpiperazines | HTR5A, HTR1A, HTR1D | KMT2A 3935/4885MEN1 4386/4885KCNQ2 1609/4885 |
| US-20070270436-A1 | NOVEL AMINO- AND IMINO-ALKYLPIPERAZINES | HTR5A, HTR1A, HTR2C | KMT2A 3556/4885MEN1 2127/4885KCNQ2 1674/4885 |
| US-20060148821-A1 | N,N-disubstituted diazocycloalkanes | HTR1A, HTR1D, HTR2C | KMT2A 4158/4885MEN1 804/4885KCNQ2 1654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.