Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773466 | 0.85 | CA1 (0.36) | SMN1; SMN2HTT | |
| SCHEMBL8716212 | 0.78 | ESR1 (0.33) | SMN1; SMN2HTT | |
| SCHEMBL18668110 | 0.77 | ESR1 (0.35) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4460667 | 0.77 | ALDH1A1 (0.52) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL499513 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL6688433 | 0.74 | MAPT (0.47) | ALDH1A1LMNASMN1; SMN2ACHEPKM | |
| SCHEMBL5179861 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL1411939 | 0.74 | ALDH1A1 (0.55) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL8713246 | 0.74 | MAPT (0.50) | ALDH1A1LMNASMN1; SMN2TDP1HPGD | |
| SCHEMBL20221449 | 0.72 | ALDH1A1 (0.48) | ALDH1A1CES2CES1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230119325-A1 | GLYCOTARGETING THERAPEUTICS | ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) (CH) | 2023-04-20 | — | — | US | disclosed |
| US-10976267-B2 | Method of analyzing diffraction data obtained from a single crystal of a porous compound and a compound for which a structure is to be determined | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2021-04-13 | — | — | US | disclosed |
| US-10953101-B2 | Glycotargeting therapeutics | ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) (CH) | 2021-03-23 | — | — | US | disclosed |
| US-10684198-B2 | Guest-compound-enveloping polymer-metal-complex crystal, method for producing same, method for preparing crystal structure analysis sample, and method for determining molecular structure of organic compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2020-06-16 | — | — | US | disclosed |
| US-10487420-B2 | Single crystal of porous compound, method for assessing quality of single crystal, method for preparing solution including compound to be analyzed, method for producing crystal structure analysis sample, and method for determining molecular structure of compound to be analyzed | THE UNIVERSITY OF TOKYO (JP) | 2019-11-26 | — | — | US | disclosed |
| US-10309035-B2 | Method of preparing sample for crystal structure analysis, method of determining absolute configuration of chiral compound, and polynuclear metal complex monocrystal | THE UNIVERSITY OF TOKYO (JP) | 2019-06-04 | — | — | US | disclosed |
| US-20190137367-A1 | GUEST-COMPOUND-ENVELOPING POLYMER-METAL-COMPLEX CRYSTAL, METHOD FOR PRODUCING SAME, METHOD FOR PREPARING CRYSTAL STRUCTURE ANALYSIS SAMPLE, AND METHOD FOR DETERMINING MOLECULAR STRUCTURE OF ORGANIC COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2019-05-09 | — | — | US | disclosed |
| US-10190952-B2 | Guest-compound-enveloping polymer-metal-complex crystal, method for producing same, method for preparing crystal structure analysis sample, and method for determining molecular structure of organic compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2019-01-29 | — | — | US | disclosed |
| EP-3269849-A1 | SINGLE CRYSTAL OF POROUS COMPOUND, METHOD FOR ASSESSING QUALITY OF SINGLE CRYSTAL, METHOD FOR PREPARING SOLUTION INCLUDING COMPOUND TO BE ANALYZED, METHOD FOR PRODUCING CRYSTAL STRUCTURE ANALYSIS SAMPLE, AND METHOD FOR DETERMINING MOLECULAR STRUCTURE OF COMPOUND TO BE ANALYZED | The University of Tokyo (JP) | 2018-01-17 | — | — | EP | disclosed |
| US-20170219500-A1 | DIFFRACTION DATA ANALYSIS METHOD, COMPUTER PROGRAM, AND RECORDING MEDIUM | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2017-08-03 | — | — | US | disclosed |
| EP-0220273-A4 | SYNTHETIC ANTIGENS FOR THE DETECTION OF AIDS-RELATED DISEASE. | GENETIC SYSTEMS CORP (US) | 1989-10-04 | — | — | EP | disclosed |
| WO-1989003813-A1 | ANTI-RETROVIRAL AGENT | GENELABS INCORPORATED (US) | 1989-05-05 | — | — | WO | disclosed |
| WO-1989003420-A1 | ANTI-RETROVIRAL AGENT | GENELABS INCORPORATED (US) | 1989-04-20 | — | — | WO | disclosed |
| WO-1989003221-A1 | ANTISYNCYTIAL AGENT | GENELABS INCORPORATED (US) | 1989-04-20 | — | — | WO | disclosed |
| EP-0284383-A1 | Synthetic antigens for the detection of aids-related disease caused by LAV-2 | GENETIC SYSTEMS CORPORATION (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0267802-A2 | Synthetic antigen for the detection of aids-related disease | GENETIC SYSTEMS CORPORATION (US) | 1988-05-18 | — | — | EP | disclosed |
| EP-0220273-A1 | SYNTHETIC ANTIGENS FOR THE DETECTION OF AIDS-RELATED DISEASE. | GENETIC SYSTEMS CORP (US) | 1987-05-06 | — | — | EP | disclosed |
| EP-0212404-A1 | 7-oxo-4-thia-1-azabicyclo [3.2.0] hept-2-ene derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |
| US-4629783-A | POLYPEPTIDES | GENETIC SYSTEMS CORPORATION (US) | 1986-12-16 | — | — | US | disclosed |
| WO-1986006414-A1 | SYNTHETIC ANTIGENS FOR THE DETECTION OF AIDS-RELATED DISEASE | GENETIC SYSTEMS CORPORATION (US) | 1986-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10190952-B2 | Guest-compound-enveloping polymer-metal-complex crystal, method for producing same, method for preparing crystal structure analysis sample, and method for determining molecular structure of organic compound | MLEC, MCM4, PICALM | ALDH1A1 4366/4885CES2 2322/4885CES1 3386/4885 |
| US-10684198-B2 | Guest-compound-enveloping polymer-metal-complex crystal, method for producing same, method for preparing crystal structure analysis sample, and method for determining molecular structure of organic compound | TPR, MCM6, MCM5 | ALDH1A1 4624/4885CES2 3121/4885CES1 4670/4885 |
| US-20190137367-A1 | GUEST-COMPOUND-ENVELOPING POLYMER-METAL-COMPLEX CRYSTAL, METHOD FOR PRODUCING SAME, METHOD FOR PREPARING CRYSTAL STRUCTURE ANALYSIS SAMPLE, AND METHOD FOR DETERMINING MOLECULAR STRUCTURE OF ORGANIC COMPOUND | TPR, MCM6, MCM5 | ALDH1A1 4624/4885CES2 3121/4885CES1 4670/4885 |
| US-20230119325-A1 | GLYCOTARGETING THERAPEUTICS | LGALS3BP, LGALS1, CD47 | ALDH1A1 1840/4885CES2 1557/4885CES1 696/4885 |
| US-10953101-B2 | Glycotargeting therapeutics | LGALS3BP, LGALS1, CD47 | ALDH1A1 1840/4885CES2 1557/4885CES1 696/4885 |
| US-10487420-B2 | Single crystal of porous compound, method for assessing quality of single crystal, method for preparing solution including compound to be analyzed, method for producing crystal structure analysis sample, and method for determining molecular structure of compound to be analyzed | CXCR5, CXCR6, CXCR1 | ALDH1A1 4527/4885CES2 4142/4885CES1 4732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.