Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10395205 | 0.84 | TSHR (0.60) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL15438304 | 0.82 | TSHR (0.46) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL13537806 | 0.82 | GAA (0.44) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL11087789 | 0.81 | TSHR (0.56) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL19512090 | 0.79 | GAA (0.46) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL10785310 | 0.79 | TSHR (0.65) | TSHRPPARD | |
| SCHEMBL28821812 | 0.79 | TSHR (0.65) | TSHRPPARDALDH1A1 | |
| SCHEMBL8683146 | 0.79 | TSHR (0.56) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL9844531 | 0.78 | TSHR (0.62) | TSHRPPARD | |
| SCHEMBL5961215 | 0.78 | TSHR (1.00) | TSHRGAAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0102115-B1 | POLYESTER-ESTER URETHANE | AKZO N.V. (NL) | 1987-06-10 | — | — | EP | claimed |
| EP-0159053-A1 | Polyester-ester urethane | AKZO N.V. (NL) | 1985-10-23 | — | — | EP | claimed |
| US-4483970-A | BLOCK POLYMERS, MOLDING MATERIALS | AKZO N.V. (NL) | 1984-11-20 | — | — | US | claimed |
| EP-0102115-A1 | Polyester-ester urethane | AKZO N.V. (NL) | 1984-03-07 | — | — | EP | claimed |
| US-20070249862-A1 | Process for the Production of Polyisocyanate/Polysilicic Acid Based Resins with Widely Variable Processability and Setting Periods | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2007-10-25 | — | — | US | disclosed |
| US-6660764-B2 | Telomerase inhibitors such as trans-3-(benzothien-6-yl)-but-2-enoic acid-N-(2-carboxy-phenyl)-amide; use as antitumor agent | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-12-09 | — | — | US | disclosed |
| US-20020123509-A1 | Carboxylic acid amides, pharmaceutical compositions containing these compounds, their use and the preparation thereof | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-09-05 | — | — | US | disclosed |
| US-5191113-A | Enzyme inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-03-02 | — | — | US | disclosed |
| EP-0291247-B1 | NOVEL CINNAMOYLAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-5093366-A | Alpha-reductase inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| US-5037852-A | Treating or reverting hair loss, acne or prostatic hypertrophy | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0291247-A2 | Novel cinnamoylamide derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-11-17 | — | — | EP | disclosed |
| US-4493846-A | Bicyclooctane derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-01-15 | — | — | US | disclosed |
| EP-0036730-B1 | BICYCLOOCTANE DERIVATIVES, PROCESSES FOR PRODUCING THEM, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, THEIR USE AS PHARMACEUTICALS AND PRECURSORS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-01-02 | — | — | EP | disclosed |
| US-4483970-A | BLOCK POLYMERS, MOLDING MATERIALS | AKZO N.V. (NL) | 1984-11-20 | — | — | US | disclosed |
| EP-0102115-A1 | Polyester-ester urethane | AKZO N.V. (NL) | 1984-03-07 | — | — | EP | disclosed |
| EP-0013461-B1 | PROCESS FOR THE PREPARATION OF A SEGMENTED THERMOPLASTIC ELASTOMER | AKZO N.V. (NL) | 1983-04-06 | — | — | EP | disclosed |
| EP-0036730-A2 | Bicyclooctane derivatives, processes for producing them, pharmaceutical compositions containing them, their use as pharmaceuticals and precursors thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-09-30 | — | — | EP | disclosed |
| EP-0013461-A1 | Process for the preparation of a segmented thermoplastic elastomer | AKZO N.V. (NL) | 1980-07-23 | — | — | EP | disclosed |
| US-4021461-A | INSECTICIDES | ZOECON CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020123509-A1 | Carboxylic acid amides, pharmaceutical compositions containing these compounds, their use and the preparation thereof | ASS1, ADCY1, ADCY3 | TSHR 2412/4885MGAM 2620/4885GAA 344/4885 |
| US-20070249862-A1 | Process for the Production of Polyisocyanate/Polysilicic Acid Based Resins with Widely Variable Processability and Setting Periods | ME1, PICALM, CA6 | TSHR 3941/4885MGAM 20/4885GAA 545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.