Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480364 | 0.86 | ALDH1A1 (0.51) | POLBSMN1; SMN2MEN1KMT2ASIRT1 | |
| SCHEMBL5470632 | 0.82 | POLB (0.51) | POLBSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL5480222 | 0.81 | POLB (0.57) | POLBSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL5477807 | 0.72 | POLB (0.55) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9819255 | 0.69 | HSD17B10 (0.57) | SMN1; SMN2MEN1KMT2AKDM4ETSHR | |
| SCHEMBL5482627 | 0.69 | POLB (0.53) | POLBMEN1KMT2AHDAC6KDM4E | |
| SCHEMBL5474190 | 0.69 | ENPP2 (0.51) | POLBSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL5470258 | 0.68 | KDM4E (0.48) | POLBMEN1KMT2AKDM4ETSHR | |
| SCHEMBL5484204 | 0.68 | SMN1; SMN2 (0.48) | POLBSMN1; SMN2MEN1KMT2ASIRT1 | |
| SCHEMBL9494443 | 0.68 | PKM (0.43) | POLBSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010529-A1 | Nitrogenous heterocyclic compounds and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010529-A1 | Nitrogenous heterocyclic compounds and medical use thereof | MAPK1, NOS1, NOS2 | POLB 2709/4885SMN1; SMN2 1822/4885MEN1 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.