Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5486419 | 0.85 | CYP2C19 (0.58) | CYP2C19SMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL12978193 | 0.84 | LMNA (0.56) | SMN1; SMN2RAB9ANPC1LMNAHIF1A | |
| SCHEMBL5077141 | 0.78 | THRB (0.56) | SMN1; SMN2RAB9ANPC1TP53ALDH1A1 | |
| SCHEMBL10285642 | 0.77 | CCNT1 (0.64) | CDK9 | |
| SCHEMBL10241771 | 0.76 | CDK9 (0.65) | SMN1; SMN2KMT2AMEN1CDK9 | |
| SCHEMBL1946717 | 0.76 | CCNT1 (0.63) | CDK9 | |
| SCHEMBL5483909 | 0.75 | SMN1; SMN2 (0.53) | CYP2C19SMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL4037864 | 0.71 | KCNH3 (0.56) | RAB9ACDK9GSK3A | |
| SCHEMBL12978212 | 0.71 | SMN1; SMN2 (0.53) | SMN1; SMN2TP53LMNAHIF1AGAA | |
| SCHEMBL2300598 | 0.70 | HRH4 (0.51) | SMN1; SMN2RAB9ANPC1TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |