Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.53 |
| ▸ | TP53 | P04637 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5486419 | 0.78 | CYP2C19 (0.58) | SMN1; SMN2TP53RAB9ANPC1MAPT | |
| SCHEMBL5483905 | 0.75 | CYP2C19 (0.54) | SMN1; SMN2TP53RAB9ANPC1MAPT | |
| SCHEMBL12978160 | 0.71 | LMNA (0.64) | SMN1; SMN2RAB9ANPC1GAALMNA | |
| SCHEMBL2300600 | 0.70 | MAPK7 (0.48) | SMN1; SMN2TP53RAB9ANPC1MAPT | |
| SCHEMBL23405908 | 0.70 | LMNA (0.66) | SMN1; SMN2TP53RAB9ANPC1LMNA | |
| SCHEMBL4072949 | 0.70 | S1PR1 (0.49) | TP53LMNA | |
| SCHEMBL1571386 | 0.69 | LMNA (1.00) | RAB9ANPC1GAALMNAHIF1A | |
| SCHEMBL3345597 | 0.69 | NPC1 (0.48) | SMN1; SMN2TP53RAB9ANPC1MAPT | |
| SCHEMBL3637857 | 0.69 | NPSR1 (0.75) | SMN1; SMN2TP53RAB9ANPC1MAPT | |
| SCHEMBL5083468 | 0.69 | ALDH1A1 (0.65) | SMN1; SMN2TP53RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |