Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5486756 | 1.00 | NFE2L2 (0.48) | NFE2L2RELACA1CYP2C9CYP3A4 | |
| SCHEMBL3950302 | 0.87 | AHR (0.35) | NFE2L2CYP2C9CYP3A4CYP2C19FBP1 | |
| SCHEMBL1104736 | 0.78 | NFE2L2 (0.50) | NFE2L2RELACA1CYP2C9CYP3A4 | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1305580 | 0.76 | NFE2L2 (0.74) | NFE2L2RELACA1CYP2C9CYP3A4 | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1793692 | 0.76 | NFE2L2 (0.74) | NFE2L2RELACA1CYP2C9CYP3A4 | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1305582 | 0.76 | NFE2L2 (0.74) | NFE2L2RELACA1CYP2C9CYP3A4 | |
| SCHEMBL318786 | 0.76 | NFE2L2 (0.74) | NFE2L2RELACA1CYP2C9CYP3A4 | |
| SCHEMBL318785 | 0.76 | NFE2L2 (0.74) | NFE2L2RELACA1CYP2C9CYP3A4 | |
| SCHEMBL2045920 | 0.75 | MAOB (0.50) | NFE2L2CA1CYP2C9ALOX5RAB9A | |
| SCHEMBL2045922 | 0.75 | MAOB (0.50) | NFE2L2CA1CYP2C9ALOX5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |