Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL16417161 | 0.90 | PTGER1 (0.48) | PDE5ANPSR1GAAPTGER1HSD17B10 | |
| SCHEMBL11888545 | 0.84 | CYP11B2 (0.48) | PDE5ANPSR1GAAPTGER1HSD17B10 | |
| SCHEMBL22206289 | 0.84 | LMNA (0.47) | PDE5ANPSR1PTGER1CCNA2CDK2 | |
| SCHEMBL5493910 | 0.84 | PTGER1 (0.59) | NPSR1PTGER1CCNA2CDK2KMT2A | |
| SCHEMBL9876889 | 0.84 | CCNE1 (0.46) | PDE5ANPSR1GAAPTGER1HSD17B10 | |
| SCHEMBL11888546 | 0.83 | PTGER1 (0.54) | NPSR1GAAPTGER1HSD17B10KMT2A | |
| SCHEMBL22214575 | 0.83 | ALDH1A1 (0.45) | PDE5ANPSR1PTGER1MAPTALDH1A1 | |
| SCHEMBL5491686 | 0.82 | L3MBTL1 (0.49) | PDE5ANPSR1GAACCNA2CDK2 | |
| SCHEMBL22214568 | 0.82 | ALDH1A1 (0.44) | PDE5ANPSR1PTGER1CCNA2CDK2 | |
| SCHEMBL22214570 | 0.82 | ALDH1A1 (0.44) | PDE5ANPSR1PTGER1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11678499-B2 | Use of singlet-triplet gap hosts for increasing stability of blue phosphorescent emission | UNIVERSAL DISPLAY CORPORATION (US) | 2023-06-13 | — | — | US | disclosed |
| US-7276627-B2 | One pot sequential reactions and novel products produced thereby | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20060224017-A1 | One pot sequential reactions and novel products produced thereby | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2006-10-05 | — | — | US | disclosed |
| US-20040077019-A1 | Tagging compounds and process for use in aida libraries | GSTACH HUBERT (AT) | 2004-04-22 | — | — | US | disclosed |
| US-6083969-A | 2,3-DIARYLPYRAZOLES FUSED WITH CYCLOALKANES AND CYCLOALKENES, USED AS CYCLOOXYGENASE-2 (COX-2) INHIBITOR | ORTHO-MCNEIL PHARACEUTICAL, INC. (US) | 2000-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060224017-A1 | One pot sequential reactions and novel products produced thereby | PNMT, CYP1A1, TERT | PDE5A 2316/4885NPSR1 1059/4885GAA 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.