Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14450473 | 0.81 | GABRB3 (0.43) | GABRB3GABRA1GABRG2 | |
| SCHEMBL14450521 | 0.76 | GRB2 (0.41) | GABRB3GABRA1GABRG2 | |
| SCHEMBL14450546 | 0.76 | GABRA1 (0.43) | GABRB3GABRA1GABRG2 | |
| SCHEMBL2525989 | 0.75 | ADRA2A (0.42) | GABRB3GABRA1GABRG2 | |
| SCHEMBL22587376 | 0.73 | GABRB3 (0.50) | GABRB3GABRA1GABRG2 | |
| SCHEMBL2535263 | 0.73 | KIF11 (0.42) | GABRB3GABRA1GABRG2 | |
| SCHEMBL5497635 | 0.71 | POLB (0.40) | GABRB3GABRA1GABRG2 | |
| SCHEMBL29738521 | 0.71 | IDO1 (0.41) | — | |
| SCHEMBL3591051 | 0.71 | IDO1 (0.41) | — | |
| SCHEMBL23860299 | 0.69 | KIF11 (0.45) | GABRB3GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070161542-A1 | Ptb1b photoprobes | RAMACHANDRAN CHIDAMBARAM | 2007-07-12 | — | — | US | disclosed |
| US-20070161542-A1 | Ptb1b photoprobes | RAMACHANDRAN CHIDAMBARAM | 2007-07-12 | — | — | US | disclosed |
| US-20070161542-A1 | Ptb1b photoprobes | RAMACHANDRAN CHIDAMBARAM | 2007-07-12 | — | — | US | disclosed |
| WO-2005056582-A1 | PTP1B PHOTOPROBES | MERCK FROSST CANADA LTD. (CA) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161542-A1 | Ptb1b photoprobes | PTBP1, PTBP3, PPP1R1B | GABRB3 1178/4885GABRA1 2397/4885GABRG2 2486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.