SCHEMBL5487845

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8399356	0.85	ALDH1A1 (0.59)	ALDH1A1TSHRSLC6A3HSD17B10MAPT
	SCHEMBL5481768	0.83	KDM4E (0.65)	ALDH1A1TSHRHSD17B10MAPTHTT
	SCHEMBL1280991	0.83	POLB (0.64)	ALDH1A1TSHRSLC6A3MAPTHTT
	SCHEMBL3783343	0.83	ALDH1A1 (0.58)	ALDH1A1TSHRSLC6A3HSD17B10MAPT
	SCHEMBL20235217	0.83	NPC1 (0.63)	ALDH1A1TSHRSLC6A3HSD17B10MAPK10
	SCHEMBL27524567	0.82	ALDH1A1 (0.57)	ALDH1A1TSHRSLC6A3HSD17B10MAPT
	SCHEMBL15285430	0.82	NPC1 (0.71)	ALDH1A1TSHRMAPTHTTCYP2C9
	SCHEMBL6538497	0.81	ALDH1A1 (0.56)	ALDH1A1TSHRSLC6A3HSD17B10MAPK10
	SCHEMBL8379922	0.81	ALDH1A1 (0.56)	ALDH1A1TSHRSLC6A3MAPTHTT
	SCHEMBL1989129	0.80	HCRTR1 (0.65)	ALDH1A1TSHRSLC6A3MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.