SCHEMBL3783343

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3786677	0.90	ALDH1A1 (0.53)	ALDH1A1TSHRMCL1KMT2ACYP1A2
	SCHEMBL8399356	0.88	ALDH1A1 (0.59)	ALDH1A1TSHRSLC6A3KMT2ACYP1A2
	SCHEMBL7897849	0.87	ABCB1 (0.61)	ALDH1A1TSHRSLC6A3HSP90AA1MAPT
	SCHEMBL3793813	0.87	ALDH1A1 (0.51)	ALDH1A1TSHRMCL1KMT2ACYP1A2
	SCHEMBL1280991	0.86	POLB (0.64)	ALDH1A1TSHRSLC6A3KMT2ACYP1A2
	SCHEMBL11286223	0.86	LMNA (0.60)	ALDH1A1MCL1KMT2ACYP1A2MEN1
	SCHEMBL4237868	0.86	KDM4E (0.65)	ALDH1A1TSHRMCL1KMT2AMEN1
	SCHEMBL29938478	0.86	LMNA (0.60)	ALDH1A1MCL1KMT2ACYP1A2MEN1
	SCHEMBL19979782	0.86	ALDH1A1 (0.50)	ALDH1A1TSHRMCL1KMT2ACYP1A2
	SCHEMBL31425872	0.86	ALDH1A1 (0.52)	ALDH1A1TSHRMCL1SLC6A3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.