Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzofuran SCHEMBL29006510 | 0.81 | MEN1 (0.39) | MAOBMAOAHDAC3LMNA | |
| Biphenyl SCHEMBL1725384 | 0.77 | CA2 (0.47) | CA2CA12CA1CA5ACA7 | |
| Benzofuran SCHEMBL5860505 | 0.77 | MAOA (0.39) | CA2CA12MAOBMAOACA1 | |
| Benzofuran SCHEMBL27730247 | 0.76 | ALDH1A1 (0.40) | MAOBMAOALMNA | |
| Benzofuran SCHEMBL11148189 | 0.76 | CA2 (0.43) | CA2CA12MAOBMAOACA1 | |
| Benzofuran SCHEMBL28385283 | 0.74 | CTNNB1 (0.43) | MAOBMAOAHDAC3LMNA | |
| Benzofuran SCHEMBL9735995 | 0.73 | MAOA (0.41) | CA2CA12MAOBMAOACA1 | |
| Acridine SCHEMBL7126489 | 0.73 | TLR8 (0.50) | CA2 | |
| Benzofuran SCHEMBL28217433 | 0.72 | CA2 (0.41) | CA2CA12MAOBMAOACA1 | |
| Benzofuran SCHEMBL8100958 | 0.71 | MAOA (0.42) | CA2CA12MAOBMAOACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845083-A2 | New arylsulfonohydrazide inhibitors of enzymes MurC and MurD | UNIVERZA V LJUBLJANI, FAKULTETA ZA FARMACIJO (SI) | 2007-10-17 | — | — | EP | disclosed |