Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPN | P05981 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.33 |
| ▸ | GLRB | P48167 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23138994 | 0.80 | MAPT (0.34) | SMN1; SMN2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL3122451 | 0.78 | ALOX5 (0.45) | PTGS1PTGS2ALOX5CA2CA1 | |
| SCHEMBL2789011 | 0.78 | GLRA3 (0.56) | PTGS1PTGS2ALOX5CA2CA1 | |
| SCHEMBL10458409 | 0.77 | ALDH1A1 (0.36) | PTGS1PTGS2ALOX5SMN1; SMN2ALDH1A1 | |
| SCHEMBL9047877 | 0.75 | TP53 (0.39) | PTGS2CA2CA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10459605 | 0.75 | GABRA1 (0.33) | PTGS1PTGS2ALOX5POLBCYP1A2 | |
| SCHEMBL13542534 | 0.74 | HTR2C (0.34) | MAPTKDM4E | |
| SCHEMBL6767336 | 0.72 | MAOA (0.39) | ALOX5 | |
| SCHEMBL23138993 | 0.71 | PTGS1 (0.34) | PTGS1PTGS2MAPTKDM4E | |
| SCHEMBL8863791 | 0.71 | CA2 (0.36) | PTGS1PTGS2ALOX5CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066681-A1 | Pharmaceutical composition for treating fatty liver or hepatic disease | CHUGAI SEIYAKU KAUSHIKI KAISHA (JP) | 2007-03-22 | — | — | US | disclosed |
| EP-1666035-A1 | MEDICINAL COMPOSITION FOR TREATMENT FOR FATTY LIVER OR LIVER DISEASE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-06-07 | — | — | EP | disclosed |
| US-20050159476-A1 | Pharmaceutical composition for preventing or treating respiratory disease | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-07-21 | — | — | US | disclosed |
| EP-1490048-A4 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2005-06-01 | — | — | EP | disclosed |
| EP-1490048-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2004-12-29 | — | — | EP | disclosed |
| US-20030195246-A1 | Seamless soft capsule preparations containing dihydrobenzofuran derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-10-16 | — | — | US | disclosed |
| WO-2003082264-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-10-09 | — | — | WO | disclosed |
| EP-1314424-A1 | SEAMLESS SOFT CAPSULE PREPARATIONS CONTAINING DIHYDROBENZOFURAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-6440999-B1 | Intimal thickening inhibitory agent | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-08-27 | — | — | US | disclosed |
| US-6417225-B1 | HYDROQUINONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-09 | — | — | US | disclosed |
| EP-0950405-A1 | REMEDIES FOR RENAL DISEASES AND ORGAN-PRESERVING AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-10-20 | — | — | EP | disclosed |
| EP-0665208-B1 | 4-ALKOXY-2,6-DI-t-BUTYLPHENOL DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0868913-A1 | INTIMAL THICKENING INHIBITOR | Chugai Seiyaku Kabushiki Kaisha (JP) | 1998-10-07 | — | — | EP | disclosed |
| US-5663373-A | ANTIISCHEMIC AGENTS AND ANTIOXIDANTS FORMED IN MULTISTAGE REACTION WITH GRIGNARD REAGENT WITH ALDEHYDE, DISSOLVING, ACIDIFICATION, DEPROTECTION AND CYCLIZATION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5606089-A | ANTIISCHEMIC AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-02-25 | — | — | US | disclosed |
| US-5574178-A | CHEMICAL INTERMEDIATES FOR OXIDATION RESISTANCE AND ANTIISCHEMIC AGENTS FORMED BY MULTISTAGE CYCLIZATION OF ALDEHYDE-ALCOHOL | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-11-12 | — | — | US | disclosed |
| US-5574178-A | CHEMICAL INTERMEDIATES FOR OXIDATION RESISTANCE AND ANTIISCHEMIC AGENTS FORMED BY MULTISTAGE CYCLIZATION OF ALDEHYDE-ALCOHOL | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-11-12 | — | — | US | disclosed |
| WO-1996022089-A1 | p-HETEROATOM-SUBSTITUTED PHENOLS AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 1996-07-25 | — | — | WO | disclosed |
| CN-1112115-A | 4-alkoxy-2, 6-di-tert-butylphenol derivative | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1995-11-22 | — | — | CN | disclosed |
| EP-0665208-A1 | 4-ALKOXY-2,6-DI-t-BUTYLPHENOL DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1995-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159476-A1 | Pharmaceutical composition for preventing or treating respiratory disease | CFTR, CMA1, SLC5A1 | PTGS1 60/4885PTGS2 612/4885ALOX5 485/4885 |
| US-20030195246-A1 | Seamless soft capsule preparations containing dihydrobenzofuran derivatives | CYP2D6, CYP2F1, SULT2A1 | PTGS1 1017/4885PTGS2 988/4885ALOX5 340/4885 |
| US-20070066681-A1 | Pharmaceutical composition for treating fatty liver or hepatic disease | LIPC, CPT1A, FABP1 | PTGS1 590/4885PTGS2 792/4885ALOX5 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.