Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.30 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9230556 | 0.79 | — | — | |
| SCHEMBL5494536 | 0.78 | ACHE (0.44) | LMNAALDH1A1SMN1; SMN2TDP1ACHE | |
| SCHEMBL18653134 | 0.77 | LMNA (0.41) | LMNATRPA1PTGS1CACNA1CTP53 | |
| SCHEMBL11057467 | 0.75 | ALDH1A1 (0.50) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL29503546 | 0.75 | ALDH1A1 (0.50) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL5490217 | 0.75 | IDO1 (0.38) | TP53NPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL5490333 | 0.74 | — | — | |
| SCHEMBL20939899 | 0.74 | TAAR1 (0.50) | LMNATRPA1PTGS1CACNA1CTP53 | |
| SCHEMBL17086648 | 0.74 | ABCB11 (0.50) | LMNATRPA1PTGS1CACNA1CTP53 | |
| SCHEMBL5484319 | 0.74 | ADRB2 (0.46) | LMNATP53TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |