Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 4/20 | 0.44 |
| ▸ | RET | P07949 | 2/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14534690 | 0.92 | NR3C1 (0.52) | NR3C1MAPK14MAPK13MAPK9MAPK12 | |
| SCHEMBL14534668 | 0.87 | NR3C1 (0.47) | NR3C1MAPK14MAPK13MAPK9MAPK12 | |
| SCHEMBL5497982 | 0.82 | MAPK14 (0.52) | NR3C1MAPK14MAPK9BRAFRAF1 | |
| SCHEMBL4409868 | 0.80 | ALDH1A1 (0.47) | MAPK14NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4551653 | 0.75 | DDR2 (0.55) | NR3C1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL14534449 | 0.74 | LMNA (0.46) | NR3C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5487329 | 0.73 | NR3C1 (0.62) | NR3C1MAPK14MAPK13MAPK9MAPK12 | |
| SCHEMBL4551652 | 0.73 | NR3C1 (0.53) | NR3C1MAPK14MAPK13MAPK9MAPK12 | |
| SCHEMBL14534466 | 0.72 | MAPK14 (0.45) | MAPK14NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4413445 | 0.71 | LMNA (0.44) | NR3C1MAPK14BRAFNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |