Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.52 |
| ▸ | SCARB1 | Q8WTV0 | 4/20 | 0.52 |
| ▸ | BRAF | P15056 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 8/20 | 0.45 |
| ▸ | GSK3A | P49840 | 8/20 | 0.45 |
| ▸ | SYK | P43405 | 7/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | LYN | P07948 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494587 | 0.86 | MAPK14 (0.42) | MAPK14BRAFSRCGSK3ASYK | |
| SCHEMBL14534690 | 0.83 | NR3C1 (0.52) | MAPK14BRAFABL1RAF1MAPK9 | |
| SCHEMBL14534668 | 0.82 | NR3C1 (0.47) | MAPK14SCARB1SRCGSK3ASYK | |
| SCHEMBL5489718 | 0.82 | NR3C1 (0.51) | MAPK14BRAFABL1RAF1MAPK9 | |
| SCHEMBL4416963 | 0.79 | MAPK14 (0.44) | MAPK14BRAFSRCGSK3ASYK | |
| SCHEMBL4417851 | 0.75 | MAPK14 (0.44) | MAPK14SCARB1SRCGSK3ASYK | |
| SCHEMBL4419919 | 0.75 | SMN1; SMN2 (0.45) | MAPK14SCARB1BRAF | |
| SCHEMBL4416273 | 0.74 | MAPK14 (0.41) | MAPK14SCARB1SRCGSK3ASYK | |
| SCHEMBL5490019 | 0.74 | RAB9A (0.42) | MAPK14GSK3A | |
| SCHEMBL4417785 | 0.74 | MAPK14 (0.43) | MAPK14BRAFGSK3ALYNMAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |