SCHEMBL2861031

SCHEMBL2861031

Cl[Si](Cl)(Cl)CCc1ccc(-c2ccc(-c3ccccc3)c3ccccc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.39
CSNK2A1 P68400 2/20 0.39
FFAR1 O14842 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HIF1A Q16665 2/20 0.37
CNR2 P34972 1/20 0.37
TAAR1 Q96RJ0 1/20 0.35
KCNH2 Q12809 1/20 0.35
HSD11B1 P28845 1/20 0.35
CDC7 O00311 1/20 0.35
ALK Q9UM73 1/20 0.35
MAPKAPK2 P49137 1/20 0.35
NPC1 O15118 1/20 0.34
KDM1A O60341 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2867556 0.96 MAOB (0.41) MAOBCSNK2A1FFAR1RXRARXRB
SCHEMBL5493502 0.87 FFAR1 (0.48) FFAR1HIF1ACNR2TAAR1KCNH2
SCHEMBL2864709 0.86 FFAR1 (0.38) FFAR1TDP1HIF1ACNR2TAAR1
SCHEMBL2865883 0.83 FFAR1 (0.36) FFAR1TDP1HIF1ATAAR1KCNH2
SCHEMBL2867796 0.81 TP53 (0.35) MAOBFFAR1TDP1HIF1AHSD11B1
SCHEMBL208903 0.78 TDP1 (0.52) MAOBTDP1TAAR1KCNH2NPC1
SCHEMBL6532094 0.76 TDP1 (0.50) MAOBTDP1TAAR1KCNH2NPC1
SCHEMBL6848455 0.76 CA2 (0.38) MAOBTDP1TAAR1ALDH1A1CYP1A2
SCHEMBL5483434 0.76 FFAR1 (0.46) MAOBFFAR1HIF1ATAAR1KCNH2
SCHEMBL2865943 0.75 ALOX5 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7749921-B2 Semiconductor element, method for manufacturing the semiconductor element, electronic device and method for manufacturing the electronic device PANASONIC CORPORATION (JP) 2010-07-06 US disclosed
US-20090194763-A1 SEMICONDUCTOR ELEMENT, METHOD FOR MANUFACTURING THE SEMICONDUCTOR ELEMENT, ELECTRONIC DEVICE AND METHOD FOR MANUFACTURING THE ELECTRONIC DEVICE PANASONIC CORPORATION (JP) 2009-08-06 US disclosed