SCHEMBL2867796

SCHEMBL2867796

Cl[Si](Cl)(Cl)CCc1ccc(-c2c3ccccc3c(-c3ccc(CC[Si](Cl)(Cl)Cl)cc3)c3ccccc23)cc1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.35
MAOB P27338 2/20 0.33
HIF1A Q16665 2/20 0.33
HTT P42858 2/20 0.33
FFAR1 O14842 1/20 0.32
NUDT1 P36639 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PTPN1 P18031 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD11B1 P28845 1/20 0.30
KDM4E B2RXH2 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
HPGD P15428 1/20 0.30
CYP2C19 P33261 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2864709 0.96 FFAR1 (0.38) TP53HIF1AFFAR1TDP1MEN1
SCHEMBL2865883 0.90 FFAR1 (0.36) TP53HIF1AFFAR1TDP1MEN1
SCHEMBL2865943 0.88 ALOX5 (0.44) L3MBTL1
SCHEMBL2867556 0.85 MAOB (0.41) MAOBHIF1AHTTFFAR1NUDT1
SCHEMBL5493502 0.82 FFAR1 (0.48) HIF1AHTTFFAR1CYP1A2
SCHEMBL2861031 0.81 MAOB (0.39) MAOBHIF1AFFAR1TDP1HSD11B1
SCHEMBL6848455 0.78 CA2 (0.38) MAOBTDP1KDM4ECYP1A2CYP2C19
SCHEMBL208903 0.77 TDP1 (0.52) MAOBTDP1CYP1A2CYP3A4HPGD
SCHEMBL6532094 0.74 TDP1 (0.50) MAOBTDP1CYP1A2CYP3A4HPGD
SCHEMBL30250264 0.74 HSD11B1 (0.41) TP53MAOBHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7749921-B2 Semiconductor element, method for manufacturing the semiconductor element, electronic device and method for manufacturing the electronic device PANASONIC CORPORATION (JP) 2010-07-06 US disclosed
US-20090194763-A1 SEMICONDUCTOR ELEMENT, METHOD FOR MANUFACTURING THE SEMICONDUCTOR ELEMENT, ELECTRONIC DEVICE AND METHOD FOR MANUFACTURING THE ELECTRONIC DEVICE PANASONIC CORPORATION (JP) 2009-08-06 US disclosed