Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | QDPR | P09417 | 3/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19880348 | 0.84 | APP (0.55) | APPALOX5MCL1ACMSDDHFR | |
| SCHEMBL13590994 | 0.80 | ALOX5 (0.62) | APPALOX5MEN1KMT2AESR2 | |
| SCHEMBL498309 | 0.80 | APP (0.67) | APPALOX5QDPRSNCAALOX15 | |
| SCHEMBL326717 | 0.78 | ALOX5 (0.64) | APPALOX5MCL1ACMSDDHFR | |
| SCHEMBL2785702 | 0.76 | MMP3 (0.55) | APPESR2ESR1 | |
| SCHEMBL8994752 | 0.76 | SNCA (0.47) | APPALOX5QDPRSNCAMEN1 | |
| SCHEMBL19314123 | 0.72 | HSD17B1 (0.55) | APPMCL1ESR2HSD17B1HSD17B2 | |
| SCHEMBL16317469 | 0.72 | MAPT (0.44) | APPMEN1ALOX15KMT2AHSD17B10 | |
| SCHEMBL27922800 | 0.72 | HSD17B1 (0.55) | MCL1ESR2HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL7125883 | 0.72 | MMP3 (0.66) | ALOX5MEN1KMT2AESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1783221-A1 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX Corp. (US) | 2007-05-09 | — | — | EP | disclosed |
| US-7001729-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. (US) | 2006-02-21 | — | — | US | disclosed |
| US-6906174-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. (US) | 2005-06-14 | — | — | US | disclosed |
| US-6906175-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor. | MIGENIX CORP. (US) | 2005-06-14 | — | — | US | disclosed |
| US-6902908-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. (US) | 2005-06-07 | — | — | US | disclosed |
| US-6887670-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. (US) | 2005-05-03 | — | — | US | disclosed |
| US-20050064530-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | MIGENIX CORP. | 2005-03-24 | — | — | US | disclosed |
| US-20050019835-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | MIGENIX CORP. | 2005-01-27 | — | — | US | disclosed |
| US-20050003353-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | MIGENIX CORP. | 2005-01-06 | — | — | US | disclosed |
| US-20050003352-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | MIGENIX CORP. | 2005-01-06 | — | — | US | disclosed |
| US-20040241801-A1 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MITOKOR, INC. | 2004-12-02 | — | — | US | disclosed |
| EP-1283884-A2 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | MITOKOR (US) | 2003-02-19 | — | — | EP | disclosed |
| US-20020012992-A1 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. | 2002-01-31 | — | — | US | disclosed |
| US-20010044144-A1 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. | 2001-11-22 | — | — | US | disclosed |
| WO-2001085944-A2 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | MITOKOR (US) | 2001-11-15 | — | — | WO | disclosed |
| WO-2000026370-A9 | ADENINE NUCLEOTIDE TRANSLOCATOR (ANT) FUSION PROTEINS AND USES THEREOF | MITOKOR (US) | 2001-11-15 | — | — | WO | disclosed |
| EP-1049780-A1 | ADENINE NUCLEOTIDE TRANSLOCATOR (ANT) FUSION PROTEINS AND USES THEREOF | MITOKOR (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-2000026370-A2 | ADENINE NUCLEOTIDE TRANSLOCATOR (ANT) FUSION PROTEINS AND USES THEREOF | MITOKOR (US) | 2000-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044144-A1 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | GART, TMEM165, SLC43A3 | APP 2124/4885ALOX5 3265/4885MCL1 4222/4885 |
| US-20050003353-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | GART, TMEM165, SLC43A3 | APP 2124/4885ALOX5 3265/4885MCL1 4222/4885 |
| US-20040241801-A1 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | GART, TMEM165, SLC43A3 | APP 2124/4885ALOX5 3265/4885MCL1 4222/4885 |
| US-20050003352-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | GART, TMEM165, SLC43A3 | APP 2124/4885ALOX5 3265/4885MCL1 4222/4885 |
| US-20050064530-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | GART, TMEM165, SLC43A3 | APP 2124/4885ALOX5 3265/4885MCL1 4222/4885 |
| US-20020012992-A1 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | GART, TMEM165, SLC43A3 | APP 2124/4885ALOX5 3265/4885MCL1 4222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.