SCHEMBL5497688

SCHEMBL5497688

CCCCCCCCCCCCCCC(C)(C)[C]=O

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GGPS1 O95749 6/20 0.41
FDPS P14324 9/20 0.40
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
SMPD1 P17405 2/20 0.39
CES2 O00748 1/20 0.39
LPAR1 Q92633 1/20 0.39
LPAR3 Q9UBY5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2368059 1.00 GGPS1 (0.41) GGPS1FDPSTSHRTHRBSMPD1
SCHEMBL5035850 1.00 GGPS1 (0.41) GGPS1FDPSTSHRTHRBSMPD1
SCHEMBL8176550 1.00 GGPS1 (0.41) GGPS1FDPSTSHRTHRBSMPD1
SCHEMBL5497444 1.00 GGPS1 (0.41) GGPS1FDPSTSHRTHRBSMPD1
SCHEMBL1410606 1.00 GGPS1 (0.41) GGPS1FDPSTSHRTHRBSMPD1
SCHEMBL424188 0.97 FDPS (0.38) GGPS1FDPSSMPD1CES2LPAR1
SCHEMBL1410618 0.90
SCHEMBL8906809 0.88 FAAH (0.50)
SCHEMBL10530613 0.81 FDPS (0.30) FDPS
SCHEMBL7722417 0.80 GGPS1 (0.41) GGPS1FDPSTSHRTHRBSMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210220258-A1 ORAL DOSAGE FORM WITH SURFACE DELIVERY OF ACTIVE AGENT ENTREGA INC. 2021-07-22 US claimed
WO-2020072729-A1 ORAL DOSAGE FORM WITH SURFACE DELIVERY OF ACTIVE AGENT ENTREGA INC. (US) 2020-04-09 WO claimed
US-20200030242-A1 ORAL DOSAGE FORM WITH DRYING AGENT FOR DELIVERY OF ACTIVE AGENT ENTREGA INC. 2020-01-30 US claimed
US-20180185440-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR DELIVERY OF BREMELANOTIDE NOVEN PHARMACEUTICALS, INC. (US) 2018-07-05 US claimed
EP-0662965-A1 1,2-DISUBSTITUTED ETHYL AMIDES AS INHIBITORS OF ACAT SCHERING CORPORATION (US) 1995-07-19 EP claimed
US-5321031-A Treating cardiovascular disorders SCHERING CORPORATION (US) 1994-06-14 US claimed
WO-1994006784-A1 1,2-DISUBSTITUTED ETHYL AMIDES AS INHIBITORS OF ACAT SCHERING CORPORATION (US) 1994-03-31 WO claimed
WO-2023215228-A1 ORAL DOSAGE FORM WITH IONICALLY CHARGEABLE HYDROGEL FOR DELIVERY OF ACTIVE AGENT ENTREGA INC. (US) 2023-11-09 WO disclosed
US-20230093875-A1 IONIC LIQUIDS FOR INTERNAL DELIVERY PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-03-30 US disclosed
US-20230040805-A1 IONIC LIQUIDS FOR INTERNAL DELIVERY PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-02-09 US disclosed
US-11446253-B2 Ionic liquids for internal delivery PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-09-20 US disclosed
US-20210220258-A1 ORAL DOSAGE FORM WITH SURFACE DELIVERY OF ACTIVE AGENT ENTREGA INC. 2021-07-22 US disclosed
EP-3709974-A1 IONIC LIQUIDS FOR INTERNAL DELIVERY President And Fellows Of Harvard College (US) 2020-09-23 EP disclosed
CN-1153526-A Concentrated cleaner compositions capable of viscosity increase upon dilution MINNESOTA MINING & MFG (US) 1997-07-02 CN disclosed
US-5607931-A AMIDES SCHERING CORPORATION (US) 1997-03-04 US disclosed
EP-0662965-A1 1,2-DISUBSTITUTED ETHYL AMIDES AS INHIBITORS OF ACAT SCHERING CORPORATION (US) 1995-07-19 EP disclosed
US-5326762-A Heterocyclic substituted amides SCHERING CORPORATION (US) 1994-07-05 US disclosed
US-5321031-A Treating cardiovascular disorders SCHERING CORPORATION (US) 1994-06-14 US disclosed
WO-1994006784-A1 1,2-DISUBSTITUTED ETHYL AMIDES AS INHIBITORS OF ACAT SCHERING CORPORATION (US) 1994-03-31 WO disclosed
US-5149709-A Treatment of atherosclerosis SCHERING CORPORATION (US) 1992-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230040805-A1 IONIC LIQUIDS FOR INTERNAL DELIVERY PNLIP, LIPA, CEL GGPS1 3459/4885FDPS 4491/4885TSHR 2333/4885
US-11446253-B2 Ionic liquids for internal delivery PNLIP, LIPA, CEL GGPS1 3459/4885FDPS 4491/4885TSHR 2333/4885
US-20180185440-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR DELIVERY OF BREMELANOTIDE VIP, MC2R, SLC10A2 GGPS1 3037/4885FDPS 4114/4885TSHR 677/4885
US-20210220258-A1 ORAL DOSAGE FORM WITH SURFACE DELIVERY OF ACTIVE AGENT SI, FABP2, SLC10A2 GGPS1 4752/4885FDPS 4072/4885TSHR 2163/4885
US-20230093875-A1 IONIC LIQUIDS FOR INTERNAL DELIVERY PNLIP, LIPA, CEL GGPS1 3459/4885FDPS 4491/4885TSHR 2333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.