Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506192 | 0.86 | MEN1 (0.37) | TDP1MAPT | |
| SCHEMBL5507821 | 0.82 | ACACB (0.39) | GAAFFAR4LMNAKDM4EMCL1 | |
| SCHEMBL5501123 | 0.79 | MAPT (0.37) | TDP1MAPT | |
| SCHEMBL5502096 | 0.79 | BRD4 (0.39) | LMNAPPARD | |
| SCHEMBL5574004 | 0.78 | KMT2A (0.39) | LMNAMCL1 | |
| SCHEMBL5501032 | 0.78 | THRA (0.40) | GAAFFAR4ALDH1A1PPARDMAPT | |
| SCHEMBL5267628 | 0.73 | PPARD (0.39) | ALDH1A1TDP1PPARDMAPT | |
| SCHEMBL5502236 | 0.73 | FFAR1 (0.38) | PPARD | |
| SCHEMBL5502760 | 0.72 | MAP2 (0.39) | ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL5501141 | 0.71 | ALDH1A1 (0.37) | GAALMNAALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |