Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252445 | 0.88 | ALDH1A1 (0.46) | MAPTTSHRHSD17B10HPGDCYP3A4 | |
| SCHEMBL5716665 | 0.88 | CYP19A1 (0.39) | MAPTTSHRNR3C1PGRAR | |
| SCHEMBL16054702 | 0.88 | CYP3A4 (0.44) | MAPTTSHRCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL5716636 | 0.85 | MAPT (0.42) | MAPTTSHRNR3C1PGRAR | |
| SCHEMBL5906064 | 0.84 | TSHR (0.47) | MAPTTSHRCYP3A4ALDH1A1NPC1 | |
| SCHEMBL5906302 | 0.82 | ALDH1A1 (0.45) | MAPTALDH1A1SMN1; SMN2L3MBTL1TXNRD1 | |
| SCHEMBL28433503 | 0.82 | MAPT (0.50) | MAPTTSHRNR3C1PGRAR | |
| SCHEMBL18458211 | 0.81 | ALDH1A1 (0.42) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL402991 | 0.81 | VCAM1 (0.51) | MAPTALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4301275 | 0.81 | VCAM1 (0.49) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104024222-A | PHTHALAMIDE DERIVATIVE, PESTICIDE FOR AGRICULTURAL AND HORTICULTURAL APPLICATIONS WHICH COMPRISES SAID DERIVATIVE, AND METHOD OF UTILIZING SAID PESTICIDE | NIHON NOHYAKU CO LTD | 2014-09-03 | — | — | CN | disclosed |
| CN-101198589-B | N-benzanilides with insecticidal activity | BAYER CROPSCIENCE AG | 2012-07-18 | — | — | CN | disclosed |
| US-8110689-B2 | Benzanilides with insecticidal activity | BAYER CROPSCIENE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| CN-102171190-A | Insecticidal benzenedicarboxamide derivative | BAYER CROPSCIENCE AG | 2011-08-31 | — | — | CN | disclosed |
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| EP-2318374-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | Bayer CropScience AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| US-20100130743-A1 | HETEROCYCLE-SUBSTITUTED, N-PHENYL-PHTHALAMIDE DERIVATIVES, RELATED COMPOUNDS AND THEIR USE AS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-05-27 | — | — | US | disclosed |
| US-20100062937-A1 | BENZANILIDES WITH INSECTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | US | disclosed |
| US-7674807-B2 | Heterocycle-substituted n-phenyl-phthalamide derivatives, related compounds and their use as insecticides | BAYER CROPSCIENCE AG (DE) | 2010-03-09 | — | — | US | disclosed |
| WO-2010012442-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2010-02-04 | — | — | WO | disclosed |
| US-20060223872-A1 | Insecticidal phthalamide derivatives | BAYER CROPSCIENCE AG (DE) | 2006-10-05 | — | — | US | disclosed |
| CN-1759105-A | Phthalamide derivatives having insecticidal activity | BAYER CROPSCIENCE AG (DE) | 2006-04-12 | — | — | CN | disclosed |
| US-7011838-B2 | Malononitrile compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-03-14 | — | — | US | disclosed |
| EP-1606271-A1 | INSECTICIDAL PHTHALAMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2005-12-21 | — | — | EP | disclosed |
| US-20050209323-A1 | Malononitrile compounds and their use as pesticides | OTAKA KEN | 2005-09-22 | — | — | US | disclosed |
| CN-1639114-A | Malononitrile compounds and their use as pesticides | SUMITOMO CHEMICAL CO (JP) | 2005-07-13 | — | — | CN | disclosed |
| WO-2004080984-A1 | INSECTICIDAL PHTHALAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2004-09-23 | — | — | WO | disclosed |
| US-20040138065-A1 | Malononitrile compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1385817-A2 | MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002090320-A2 | MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100062937-A1 | BENZANILIDES WITH INSECTICIDAL ACTIVITY | CBR3, HCN3, HAX1 | MAPT 4865/4885TSHR 926/4885NR3C1 4184/4885 |
| US-20050209323-A1 | Malononitrile compounds and their use as pesticides | C1S, C1R, C5 | MAPT 4314/4885TSHR 2542/4885NR3C1 2356/4885 |
| US-20100130743-A1 | HETEROCYCLE-SUBSTITUTED, N-PHENYL-PHTHALAMIDE DERIVATIVES, RELATED COMPOUNDS AND THEIR USE AS INSECTICIDES | DDT, SQOR, CYP2S1 | MAPT 4020/4885TSHR 1924/4885NR3C1 3575/4885 |
| US-20060223872-A1 | Insecticidal phthalamide derivatives | CRYAA, PRXL2A, H1-2 | MAPT 2074/4885TSHR 2326/4885NR3C1 4456/4885 |
| US-20040138065-A1 | Malononitrile compounds and their use as pesticides | CBR1, MAL2, CBR3 | MAPT 4612/4885TSHR 3805/4885NR3C1 906/4885 |
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | DDT, BRD9, BCL2A1 | MAPT 4079/4885TSHR 2047/4885NR3C1 4682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.