Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PORCN | Q9H237 | 6/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSB | P07858 | 4/20 | 0.41 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ADH5 | P11766 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178943 | 0.82 | CTSK (0.48) | PORCNCTSKCTSSCTSBCTSL | |
| SCHEMBL5516782 | 0.82 | CTSK (0.48) | PORCNCTSKCTSSCTSBCTSL | |
| SCHEMBL6001121 | 0.81 | CTSB (0.53) | CTSKCTSSCTSBCTSL | |
| SCHEMBL4700947 | 0.79 | CTSL (0.66) | CTSKCTSSCTSBCTSL | |
| SCHEMBL6172215 | 0.79 | CTSK (0.58) | CTSKCTSSCTSBCTSL | |
| SCHEMBL4700794 | 0.76 | CTSS (0.62) | CTSKCTSSCTSBCTSL | |
| SCHEMBL5514860 | 0.75 | CTSS (0.44) | CTSKCTSSCTSBCTSL | |
| SCHEMBL4700791 | 0.74 | CTSS (0.45) | CTSKCTSSCTSBCTSL | |
| SCHEMBL4699259 | 0.73 | CTSK (0.60) | CTSKCTSSCTSBCTSL | |
| SCHEMBL6208701 | 0.72 | CTSS (0.48) | CTSKCTSSCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279478-B2 | Cathepsin cysteine protease inhibitors | MERCK FROSST CANADA & CO. (CA) | 2007-10-09 | — | — | US | disclosed |