SCHEMBL5529154

SCHEMBL5529154

NCCCCCCn1cncc1C(N)=O

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 2/20 0.33
PAOX Q6QHF9 1/20 0.32
TGFBR1 P36897 1/20 0.32
QPCT Q16769 8/20 0.32
CYP3A4 P08684 1/20 0.31
TBXAS1 P24557 1/20 0.31
CHEK1 O14757 1/20 0.31
MAPKAPK2 P49137 1/20 0.31
CPB1 P15086 1/20 0.31
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7521995 0.80 TGFBR1 (0.37) TGFBR1CYP3A4
SCHEMBL31702139 0.74 CCNC (0.40) TGFBR1QPCT
SCHEMBL24791689 0.74 HTR7 (0.43) TGFBR1CYP3A4
SCHEMBL5528585 0.74 MAOA (0.48) QPCTCYP3A4
SCHEMBL3626809 0.70 QPCT (0.44) QPCT
SCHEMBL31518568 0.69 HTR1A (0.33) CYP3A4
SCHEMBL6701818 0.69 TDP1 (0.39) TBXAS1PDE4APDE4BPDE4CPDE4D
SCHEMBL9714161 0.68 CA5A (0.48) TGFBR1PDE4A
SCHEMBL10421136 0.68 F13A1 (0.40) CYP3A4
SCHEMBL2638060 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8518859-B2 Method for increasing yield of staple food crop NATIONAL UNIVERSITY CORPORATION SHIZUOKA UNIVERSITY (JP) 2013-08-27 US disclosed
US-8518859-B2 Method for increasing yield of staple food crop NATIONAL UNIVERSITY CORPORATION SHIZUOKA UNIVERSITY (JP) 2013-08-27 US disclosed
US-20120122690-A1 Method For Increasing Yield Of Staple Food Crop NATIONAL UNIVERSITY CORPORATION SHIZUOKA (JP) 2012-05-17 US disclosed
US-20120122690-A1 Method For Increasing Yield Of Staple Food Crop NATIONAL UNIVERSITY CORPORATION SHIZUOKA (JP) 2012-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120122690-A1 Method For Increasing Yield Of Staple Food Crop SI, H1-0, H1-3 CPB2 473/4885PAOX 658/4885TGFBR1 3689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.