SCHEMBL554390

SCHEMBL554390

CC(=CCc1ccccc1)C(N)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
MAOB P27338 1/20 0.41
NOS2 P35228 3/20 0.41
ALPI P09923 1/20 0.41
PKM P14618 1/20 0.41
PTGS1 P23219 1/20 0.41
XIAP P98170 1/20 0.41
SLC7A5 Q01650 1/20 0.41
CYP2C9 P11712 1/20 0.41
PLA2G10 O15496 1/20 0.40
PLA2G2A P14555 1/20 0.40
LMNA P02545 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
AKR1B1 P15121 1/20 0.39
TOP1 P11387 1/20 0.39
GAA P10253 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
AKR1C3 P42330 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL554389 1.00 ALDH1A1 (0.42) ALDH1A1MAOBNOS2ALPIPKM
SCHEMBL30528 0.84 CYP2C9 (0.51) ALDH1A1MAOBALPIPKMPTGS1
SCHEMBL19134568 0.84 ALDH1A1 (0.45) ALDH1A1MAOBALPIPKMPTGS1
SCHEMBL30530 0.84 CYP2C9 (0.51) ALDH1A1MAOBALPIPKMPTGS1
SCHEMBL3869765 0.83 CA2 (0.47) ALDH1A1SLC7A5TAAR1IDO1
SCHEMBL1788431 0.83 IDO1 (0.43) ALDH1A1MAOBLMNATAAR1IDO1
Iodide SCHEMBL3761279 0.82 CYP2C9 (0.50) ALDH1A1MAOBALPIPKMPTGS1
SCHEMBL29466950 0.82 NOS3 (0.36) ALDH1A1NOS2CYP2C9LMNAAKR1B1
SCHEMBL59798 0.82 NOS3 (0.36) ALDH1A1NOS2CYP2C9LMNAAKR1B1
SCHEMBL7664190 0.82 ALDH1A1 (0.44) ALDH1A1MAOBALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 956 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026043851-A1 MODIFIED HIGH RI POLYVINYL ACETATE EASTMAN CHEMICAL COMPANY (US) 2026-02-26 WO claimed
US-20260040695-A1 A METHOD TO GENERATE CONDUCTIVE POLYMER NEWSOUTH INNOVATIONS PTY LTD (AU) 2026-02-05 US claimed
US-20250198980-A1 COMBINATORIAL HIGH-THROUGHPUT SCREENING OF COMPLEX POLYMERIC ENZYME IMMOBILIZATION SUPPORTS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2025-06-19 US claimed
EP-4562077-A1 A METHOD TO GENERATE CONDUCTIVE POLYMER NewSouth Innovations Pty Limited (AU) 2025-06-04 EP claimed
WO-2024129968-A1 INJECTABLE COMPOSITIONS FOR TREATING JOINT CONDITIONS OHIO STATE INNOVATION FOUNDATION (US) 2024-06-20 WO claimed
WO-2024020649-A1 A METHOD TO GENERATE CONDUCTIVE POLYMER NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2024-02-01 WO claimed
WO-2023215886-A1 ENGINEERED PARTICLES AS RED BLOOD CELL MIMICS AND COMPOSITIONS CONTAINING SAME FOR HEMATOLOGY SLINGSHOT BIOSCIENCES, INC. (US) 2023-11-09 WO claimed
WO-2023116955-A1 WATER-BORNE HYBRID VARNISH AND THE METHOD OF ITS PREPARATION Centrum organické chemie s.r.o. (CZ) 2023-06-29 WO claimed
WO-2022261721-A1 HEALABLE AND REPROCESSABLE COMPOSITIONS DEAKIN UNIVERSITY (AU) 2022-12-22 WO claimed
CN-114958493-A Automatic dishwasher detergent composition for improving tableware quick-drying performance 广州立涤科技有限公司 2022-08-30 CN claimed
US-20060122349-A1 Making high refractive index copolymer by sonicating mixture of carbazole or naphthyl moiety, naphthyl group monomer, hydrophobic monomer, hydrophillic monomer, and crosslinker; soft, optically transparent, high refractive index materials particularly suited for use in intraocular, contact lenses KEY MEDICAL TECHNOLOGIES, INC. (US) 2006-06-08 US claimed
EP-1660153-A2 HYDROGEL NANOCOMPSITES FOR OPHTHALMIC APPLICATIONS The United States of America as represented by the Department of Veterans Affairs (US) 2006-05-31 EP claimed
US-20060074142-A1 Aqueous inks containing colored polymers XEROX CORPORATION 2006-04-06 US claimed
WO-2006034575-A1 COMPOSITE MATERIAL COMPRISING LAYERED HYDROPHILIC COATINGS MCMASTER UNIVERSITY (CA) 2006-04-06 WO claimed
WO-2005023331-A2 HYDROGEL NANOCOMPSITES FOR OPHTHALMIC APPLICATIONS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) 2005-03-17 WO claimed
US-20040156880-A1 Reversible hydrogel systems and methods therefor DEPARTMENT OF VETERANS AFFAIRS, THE 2004-08-12 US claimed
US-6190825-B1 N-(P-AMINOSULFONYL)PHENYL-SUBSTITUTED AGFA-GEVAERT N.V. (BE) 2001-02-20 US claimed
WO-2000034804-A1 HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-06-15 WO claimed
US-5352365-A Process for removing scale, and reducing scale formation in sewage treatment plants FULLER RICHARD L (US) 1994-10-04 US claimed
WO-1988005791-A1 RADIATION-CURED ADHESIVE SYSTEM CONTAINING AMIDES DYMAX CORPORATION (US) 1988-08-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260040695-A1 A METHOD TO GENERATE CONDUCTIVE POLYMER PIEZO1, LCP1, MTCL3 ALDH1A1 4717/4885MAOB 4633/4885NOS2 465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.