Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | GPR3 | P46089 | 2/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11010626 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 | |
| SCHEMBL208833 | 0.73 | DAO (0.46) | ALDH1A1KDM4ELMNAHPGDSMN1; SMN2 | |
| SCHEMBL208837 | 0.73 | DAO (0.46) | ALDH1A1KDM4ELMNAHPGDGLA | |
| SCHEMBL208230 | 0.73 | LMNA (0.42) | ALDH1A1KDM4ELMNAHPGDGAA | |
| SCHEMBL207151 | 0.73 | METAP2 (0.46) | LMNAHPGDCHEK1 | |
| SCHEMBL208047 | 0.73 | FLT3 (0.46) | ALDH1A1LMNAHPGDHSD17B10MAPT | |
| SCHEMBL14974362 | 0.72 | KDM4E (0.47) | ALDH1A1KDM4ELMNAHPGDGLA | |
| SCHEMBL9384243 | 0.71 | PARP1 (0.44) | ALDH1A1PARP1MEN1KMT2AMAPT | |
| SCHEMBL210679 | 0.70 | TYMS (0.37) | — | |
| SCHEMBL207339 | 0.70 | LOXL2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160517-B1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE LYON (FR) | 2024-06-12 | — | — | EP | claimed |
| EP-3555112-B1 | FLUOROGENIC GLYCOSIDASE SUBSTRATE AND ASSOCIATED DETECTION METHOD | ECOLE NORMALE SUPERIEURE LYON (FR) | 2023-12-06 | — | — | EP | claimed |
| US-20230158028-A1 | COMPOUNDS AND METHODS FOR INDUCING UCP1 EXPRESSION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-25 | — | — | US | claimed |
| EP-4132914-A1 | COMPOUNDS AND METHODS FOR INDUCING UCP1 EXPRESSION | The Regents of the University of California (US) | 2023-02-15 | — | — | EP | claimed |
| EP-3555112-A1 | FLUOROGENIC GLYCOSIDASE SUBSTRATE AND ASSOCIATED DETECTION METHOD | Ecole Normale Superieure De Lyon (FR) | 2019-10-23 | — | — | EP | claimed |
| US-10179929-B2 | Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2019-01-15 | — | — | US | claimed |
| EP-2760844-B1 | FLUOROGENIC PEPTIDASE SUBSTRATE | ECOLE NORMALE SUPERIEURE LYON (FR) | 2018-11-21 | — | — | EP | claimed |
| EP-2318355-B1 | 1,1'-DIADAMANTYL CARBOXYLIC ACIDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | BOEHRINGER INGELHEIM INT (DE) | 2018-09-12 | — | — | EP | claimed |
| EP-2496559-B1 | ARYL- AND HETEROARYLCARBONYL DERIVATIVES OF HEXAHYDROINDENOPYRIDINE AND OCTAHYDROBENZOQUINOLINE AND THEIR USE AS HSD 1 INHIBITORS | VITAE PHARMACEUTICALS INC (US) | 2018-01-10 | — | — | EP | claimed |
| EP-2350068-B1 | UREA DERIVATIVES OF SUBSTITUTED NORTROPANES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | BOEHRINGER INGELHEIM INT (DE) | 2017-08-30 | — | — | EP | claimed |
| EP-0137177-B1 | CHROMOGENE AND FLUOROGENE CARBOXYLIC-ACID ESTERS, METHOD FOR THEIR PREPARATION AND AGENTS FOR THE DETECTION AND DETERMINATION OF HYDROLASES | BAYER AG (DE) | 1987-10-28 | — | — | EP | claimed |
| EP-0224687-A1 | Metal complex pigments | BAYER AG (DE) | 1987-06-10 | — | — | EP | claimed |
| EP-0223162-A2 | Glycosides, process for their preparation, and process and a means for the detection and photometric and fluorometric determination of sugar-cleaving enzymes (glycosidases) | BAYER AG (DE) | 1987-05-27 | — | — | EP | claimed |
| US-4659657-A | Chromogenic and fluorogenic esters for photometric or fluorimetric determination of phosphatases or sulphatases | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | claimed |
| EP-0056157-B1 | USE OF 7-HYDROXY-COUMARIN COMPOUNDS FOR IMPREGNATING PAPER | BAYER AG (DE) | 1985-05-29 | — | — | EP | claimed |
| EP-0137177-A1 | Chromogene and fluorogene carboxylic-acid esters, method for their preparation and agents for the detection and determination of hydrolases | BAYER AG (DE) | 1985-04-17 | — | — | EP | claimed |
| US-4411946-A | FORGERY-PROOF PAPER | BAYER AKTIENGESELLSCHAFT (DE) | 1983-10-25 | — | — | US | claimed |
| EP-0003771-B1 | CARBOSTYRILE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1982-10-20 | — | — | EP | claimed |
| EP-0056157-A1 | Use of 7-hydroxy-coumarin compounds for impregnating paper | BAYER AG (DE) | 1982-07-21 | — | — | EP | claimed |
| US-4329347-A | Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril | BOEHRINGER INGELHEIM GMBH (DE) | 1982-05-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10179929-B2 | Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods | SI, GUSB, ABCG2 | ALDH1A1 426/4885KDM4E 4802/4885LMNA 398/4885 |
| US-20230158028-A1 | COMPOUNDS AND METHODS FOR INDUCING UCP1 EXPRESSION | TFAM, FABP4, CPT2 | ALDH1A1 1604/4885KDM4E 3552/4885LMNA 688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.