Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GCG | P01275 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5551857 | 0.87 | KMT2A (0.38) | KDM4EALDH1A1GCGGCGR | |
| SCHEMBL6723685 | 0.81 | PRMT6 (0.37) | — | |
| SCHEMBL5551399 | 0.80 | ALDH1A1 (0.47) | KDM4EALDH1A1 | |
| SCHEMBL5553199 | 0.78 | ALDH1A1 (0.35) | KDM4EALDH1A1HSD17B10GCGGCGR | |
| SCHEMBL5548655 | 0.71 | MAPT (0.34) | KDM4EALDH1A1 | |
| SCHEMBL5215254 | 0.70 | CYP1A2 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL5211817 | 0.70 | NPSR1 (0.38) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5551870 | 0.66 | PTGS2 (0.35) | GCGGCGR | |
| SCHEMBL6181367 | 0.65 | PRMT6 (0.38) | — | |
| SCHEMBL8126929 | 0.65 | F2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211673-B2 | 4-trifluoromethylpyrazolyl-substituted pyridines and pyrimidines | BAYER CROPSCIENCE GMBH (DE) | 2007-05-01 | — | — | US | disclosed |
| US-20060122063-A1 | 5-methyl-2-(4-trifluoromethyl-1H-1-pyrazolyl)-4-(5-trifluoromethyl-3-thienyloxy)pyrimidine; broadleaf herbicide | BAYER CROPSCIENCE GMBH (DE) | 2006-06-08 | — | — | US | disclosed |
| US-7022650-B2 | 4-trifluoromethylpyrazolyl-substituted pyridines and pyrimidines | BAYER CROPSCIENCE GMBH (DE) | 2006-04-04 | — | — | US | disclosed |
| EP-1527069-A2 | PYRIDINES AND PYRIMIDINES SUBSTITUTED BY 4-TRIFLUOROMETHYLPYRAZOLYL | Bayer CropScience GmbH (DE) | 2005-05-04 | — | — | EP | disclosed |
| US-20040072692-A1 | 4-trifluoromethylpyrazolyl-substituted pyridines and pyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-04-15 | — | — | US | disclosed |
| WO-2004013131-A2 | PYRIDINES AND PYRIMIDINES SUBSTITUTED BY 4-TRIFLUOROMETHYLPYRAZOLYL | BAYER CROPSCIENCE GMBH (DE) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072692-A1 | 4-trifluoromethylpyrazolyl-substituted pyridines and pyrimidines | CYP4X1, ROS1, NOX4 | KDM4E 1185/4885ALDH1A1 282/4885HSD17B10 3428/4885 |
| US-20060122063-A1 | 5-methyl-2-(4-trifluoromethyl-1H-1-pyrazolyl)-4-(5-trifluoromethyl-3-thienyloxy)pyrimidine; broadleaf herbicide | CYP2F1, CYP4F2, CYP4F3 | KDM4E 594/4885ALDH1A1 260/4885HSD17B10 2506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.