Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 6/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14402284 | 0.87 | ALDH1A1 (0.46) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL175987 | 0.73 | ALDH1A1 (0.59) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL9319353 | 0.69 | BCL2L1 (0.46) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| Formic Acid SCHEMBL11853384 | 0.68 | ALDH1A1 (0.55) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL23909558 | 0.67 | LMNA (0.41) | KDM4EHPGDTSHRHSD17B10ALDH1A1 | |
| SCHEMBL23909517 | 0.67 | ALDH1A1 (0.37) | KDM4EHPGDHTTPKMGLA | |
| SCHEMBL20130411 | 0.67 | CYP1A2 (0.40) | KDM4EHPGDGLATSHRHSD17B10 | |
| SCHEMBL11371242 | 0.67 | AKR1B1 (0.70) | KDM4EHPGDHSD17B10ALDH1A1AKR1B1 | |
| SCHEMBL18503856 | 0.66 | KDM4E (0.49) | KDM4EHPGDTSHRHSD17B10ALDH1A1 | |
| SCHEMBL23909583 | 0.66 | ALDH1A1 (0.39) | KDM4EHPGDGLAHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121453-A2 | 2-HYDROXY-1-OXO 1,2 DIHYDRO ISOQUINOLINE CHELATING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007121453-A2 | 2-HYDROXY-1-OXO 1,2 DIHYDRO ISOQUINOLINE CHELATING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-10-25 | — | — | WO | disclosed |