Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | GRB2 | P62993 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 5/20 | 0.38 |
| ▸ | CTSD | P07339 | 2/20 | 0.37 |
| ▸ | PSMB11 | A5LHX3 | 4/20 | 0.36 |
| ▸ | PSMA7 | O14818 | 4/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.36 |
| ▸ | PSMA1 | P25786 | 4/20 | 0.36 |
| ▸ | PSMA2 | P25787 | 4/20 | 0.36 |
| ▸ | PSMA3 | P25788 | 4/20 | 0.36 |
| ▸ | PSMA4 | P25789 | 4/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.36 |
| ▸ | PSMA5 | P28066 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5556455 | 0.90 | CTSB (0.47) | CTSBCTSKMMEACECPA1 | |
| SCHEMBL5557796 | 0.82 | CTSD (0.35) | MMP3PSMB8CTSDPSMB11PSMA7 | |
| SCHEMBL5557632 | 0.82 | MMP9 (0.46) | CTSBCTSKMMP3CTSDMMP2 | |
| SCHEMBL5556531 | 0.81 | MMP2 (0.43) | MMP3CCKBRCCKARMMP2MMP9 | |
| SCHEMBL5552457 | 0.81 | KLKB1 (0.44) | MMP3CCKBRCCKARMMP2MMP9 | |
| SCHEMBL5556372 | 0.81 | KLKB1 (0.44) | MMP3CCKBRCCKARMMP2MMP9 | |
| SCHEMBL5552925 | 0.81 | MMP3 (0.47) | MMP3MMP2MMP9 | |
| SCHEMBL5552864 | 0.80 | PTPN1 (0.40) | MMP3MMP2MMP9MMP8 | |
| SCHEMBL5557641 | 0.78 | MMP9 (0.45) | LCKCTSDMMP2MMP9MMP8 | |
| SCHEMBL5552415 | 0.77 | MMP2 (0.57) | MMEACECPA1ACE2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | CENGENT THERAPEUTICS (US) | 2007-08-23 | — | — | US | disclosed |
| WO-2005027856-A2 | INHIBITORS OF ANTHRAX LETHAL FACTOR | CENGENT THERAPEUTICS (US) | 2005-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | APAF1, ANTXR2, LITAF | CTSB 239/4885CTSK 306/4885MME 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.