Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.65 |
| ▸ | CASP6 | P55212 | 3/20 | 0.49 |
| ▸ | NSD2 | O96028 | 2/20 | 0.49 |
| ▸ | NT5E | P21589 | 2/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673672 | 0.94 | SNCA (0.58) | SNCACASP6NSD2NT5EDUSP3 | |
| SCHEMBL4948579 | 0.92 | SNCA (0.56) | SNCACASP6NSD2NT5EDUSP3 | |
| SCHEMBL4948584 | 0.86 | SNCA (0.51) | SNCACASP6NSD2NT5EDUSP3 | |
| SCHEMBL4651295 | 0.84 | CASP6 (0.69) | SNCACASP6NSD2NT5EDUSP3 | |
| SCHEMBL300937 | 0.83 | SNCA (0.62) | SNCACASP6NSD2NT5EDUSP3 | |
| SCHEMBL305423 | 0.83 | SNCA (0.62) | SNCACASP6NSD2NT5EDUSP3 | |
| SCHEMBL30233294 | 0.83 | SNCA (0.62) | SNCACASP6NSD2NT5EDUSP3 | |
| SCHEMBL27263654 | 0.82 | SNCA (0.64) | SNCACASP6NSD2NT5EDUSP3 | |
| SCHEMBL141383 | 0.81 | SNCA (0.61) | SNCACASP6NT5EALDH1A1HSD17B10 | |
| SCHEMBL35747 | 0.81 | ALDH1A1 (0.61) | SNCANT5EALDH1A1HSD17B10CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282327-B2 | Nucleic acid labeling compounds | AFFYMETRIX, INC. (US) | 2007-10-16 | — | — | US | claimed |
| US-20060106102-A1 | Napththalene derivatives which inhibit the cytokine or biological activity of microphage migration inhibitory factor (mif) | Morand, Eric | 2006-05-18 | — | — | US | claimed |
| US-11524004-B2 | Analogs of proxisome proliferator activated receptor (PPAR) agonists and methods of using the same | THE UNIVERSITY OF TOLEDO (US) | 2022-12-13 | — | — | US | disclosed |
| US-20210038571-A1 | Analogs of Proxisome Proliferator Activated Receptor (PPAR) Agonists and Methods of Using the Same | THE UNIVERSITY OF TOLEDO (US) | 2021-02-11 | — | — | US | disclosed |
| US-10776461-B2 | Analogs of proxisome proliferator activated receptor (PPAR) agonists and methods of using the same | THE UNIVERSITY OF TOLEDO (US) | 2020-09-15 | — | — | US | disclosed |
| CN-110199031-A | Method for designing a set of polynucleotide sequences for analyzing specific events in a genetic region of interest | 基因组影像公司 | 2019-09-03 | — | — | CN | disclosed |
| US-20190147147-A1 | Analogs of Proxisome Proliferator Activated Receptor (PPAR) Agonists and Methods of Using the Same | THE UNIVERSITY OF TOLEDO (US) | 2019-05-16 | — | — | US | disclosed |
| US-10181018-B2 | Analogs of proxisome proliferator activated receptor (PPAR) agonists and methods of using the same | THE UNIVERSITY OF TOLEDO (US) | 2019-01-15 | — | — | US | disclosed |
| US-20160347789-A1 | Method for purification of antibodies, antibody fragments or engineered variants thereof using specific anthraquinone dye-ligand structures | BASF SE (DE) | 2016-12-01 | — | — | US | disclosed |
| US-20060194258-A1 | Polypeptide array synthesis | AFFYMETRIX, INC. (US) | 2006-08-31 | — | — | US | disclosed |
| CN-1818076-A | Nucleic acid labeling methods | AFFYMETRIX INC (US) | 2006-08-16 | — | — | CN | disclosed |
| US-20060106102-A1 | Napththalene derivatives which inhibit the cytokine or biological activity of microphage migration inhibitory factor (mif) | Morand, Eric | 2006-05-18 | — | — | US | disclosed |
| US-20050153362-A1 | Polymer arrays | PIRRUNG MICHAEL C (US) | 2005-07-14 | — | — | US | disclosed |
| US-20050153363-A1 | Polymer arrays | PIRRUNG MICHAEL C (US) | 2005-07-14 | — | — | US | disclosed |
| US-20050118706-A1 | Polymer arrays | AFFYMETRIX, INC. (US) | 2005-06-02 | — | — | US | disclosed |
| US-20050064479-A1 | Compounds and methods for post incorporation labeling of nucleic acids | AFFYMETRIX, INC. (US) | 2005-03-24 | — | — | US | disclosed |
| US-20040038268-A1 | Support bound probes and methods of analysis using the same | AFFYMETRIX, INC. | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190147147-A1 | Analogs of Proxisome Proliferator Activated Receptor (PPAR) Agonists and Methods of Using the Same | PPARG, PPARA, PPARD | SNCA 4709/4885CASP6 3189/4885NSD2 4705/4885 |
| US-11524004-B2 | Analogs of proxisome proliferator activated receptor (PPAR) agonists and methods of using the same | PPARG, PPARA, PPARD | SNCA 4709/4885CASP6 3189/4885NSD2 4705/4885 |
| US-10776461-B2 | Analogs of proxisome proliferator activated receptor (PPAR) agonists and methods of using the same | PPARG, PPARA, PPARD | SNCA 4709/4885CASP6 3189/4885NSD2 4705/4885 |
| US-20160347789-A1 | Method for purification of antibodies, antibody fragments or engineered variants thereof using specific anthraquinone dye-ligand structures | ANTXR2, FCGR3B, IGLV6-57 | SNCA 4339/4885CASP6 4380/4885NSD2 3814/4885 |
| US-10181018-B2 | Analogs of proxisome proliferator activated receptor (PPAR) agonists and methods of using the same | PPARG, PPARA, PPARD | SNCA 4709/4885CASP6 3189/4885NSD2 4705/4885 |
| US-20060194258-A1 | Polypeptide array synthesis | MRPL21, NGLY1, PSAP | SNCA 2875/4885CASP6 4155/4885NSD2 4857/4885 |
| US-20050064479-A1 | Compounds and methods for post incorporation labeling of nucleic acids | RNGTT, RNMT, DUT | SNCA 4203/4885CASP6 3861/4885NSD2 1530/4885 |
| US-20060106102-A1 | Napththalene derivatives which inhibit the cytokine or biological activity of microphage migration inhibitory factor (mif) | MIF, ARG1, MSR1 | SNCA 2976/4885CASP6 2794/4885NSD2 1150/4885 |
| US-20210038571-A1 | Analogs of Proxisome Proliferator Activated Receptor (PPAR) Agonists and Methods of Using the Same | PPARG, PPARA, PPARD | SNCA 4709/4885CASP6 3189/4885NSD2 4705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.